February Changes in BioC Devel
February 2006
affxparser
Converted publicly available methods from dot-syntax to camel case syntax (e.g., read.cel --> readCel)
Changes to make the package compile on SUN machines
It is now possible to specify what readCdfUnits should return
Addec C functions for fast querying of number of probes in probesets and groupnames in probesets
Added C function to identify which probes are PM probes
affy
Fixed sampleNames in read.affybatch to conform with row.names of the phenoData slot to match with exprSet validity checking
Added a new example dataset to allow examples for merge.AffyBatch and ppsetApply to work correctly
Fixed mva.pairs to accept cex argument for text size of statistics
Added optional smoothScatter to MAplot, etc
affycoretools
Changed plotDeg and plotHist to automatically extract sample names from the AffyBatch object
Added filterfun argument to foldFilt to allow for arbitrary filtering of probesets in addition to fold change
Bugfix in affystart that occured when one has a single chip and uses expression = "mas"
Bugfix in vennSelect that wasn't ordering HTML tables correctly when number of contrasts == 2
Moved hyperGtable and hyperG2Affy to GOstats package
affyio
Fixed code that does checking if textCDFfile
annaffy
Added all, all.x and all.y options to merge.aafTable
Added custom getHTML method to aafUniGene to fix small bug
AnnBuilder
Modification of yeastPkgBuilder to fix the bug of YEAST genename/alias
Fixed bug in KEGGENOME url
apComplex
Bugfix in sortComplexes
Changed some rownames of yNameTAP
beadarray
Improved speed of findAllOutliers and createBeadSummaryData
Improved speed of readBeadImages
Bugfix in createBeadSummaryData
Biobase
Added matchpt to fnd nearest neighbours within a matrix or vector, or to match a matrix or vector onto another
Man page updates
Fixed subsetting of exprSet and eSet so that reporterInfo is subset correctly
Added protections for exprSets with missing reporterInfo slots
biomaRt
Converting biomaRt to use RCurl
MySQL access is still possible, but access to BioMart databases is now by default via the bioMart webservices over HTTP
Added drop = FALSE tot he postprocessing of getBM result in order to be consistent if there is only one attribute
BufferedMatrix
New Package:
An experimental package for dealing with large datasets
Maintainer:
Benjamin Milo Bolstad
cellHTS
New Package:
Analysis of cell-based high-throughput screens
Maintainer:
Wolfgang Huber
copa
New Package:
COPA is a method to find genes that undergo recurrent fusion
in a given cancer type by finding pairs of genes that have
mutually exclusive outlier profiles.
Maintainer:
James W. MacDonald
gcrma
Fixed justGCRMA to conform to the new exprSet object checking in Biobase
Modified C code to make it C ANSI-compliant
GeneRfold
New Package:
Package manipulating sequences with fold routines
Maintainer:
Antoine Lucas
GEOquery
Fixed GDS2eSet to comply with the new validity checking in Biobase
Added GSElimits to getGEO to allow for parsing of large datasets in pieces
GlobalAncova
Fixed bug regarding testing one gene
GOstats
Changed GOhyperG so user can supply the universe
Moved hyperG2Affy and hyperGtable from affycoretools
graph
Fixed GXL writing for undirected graphs: no duplication of reciprocal edges
Added GXL for all graphs in the graphExamples data and a script that can be used to recreate the rda file when class defs change
Added 'edges' argument to initialize method fo graphNEL
You can now create new graphNEL instances by passing a list in the 'edges' argument to initialize
This list has the same structure as the list returned by the edges method of a graph object.
Overhaul of integration of special edge attribute 'weight' to handle addNote, removeNode, removeEdge
Fixed edgeData for undirected graphs
Fixed validation of reciprocal edges for undirected graphs
Fixed directed graph example
Refactored addNode for graphNEL
Refactored graphNEL initialization; made edgeL polymorphic
We now accept two structures for edgeL; a list similar in structure to that returned by edges(g) and a more compicated nested structure documented for edgeL
Fixed initialization of edgeL argument vector in randomGraph and randomNodeGraph
Fixed randomGraph so weights argument works
Added C code for attrDataItem access to speed up read access
iSNetwork
Added functionality to link plots of a graph
Started a vignette
iSPlot
Added a paper to the package
Updated man pages
makePlatformDesign
Bugfix in readSNPCDF and readSNPtxtCDF to correctly label PM and MM probes
Added posfile option in makePDpackage; useful for NGS data, in order to update the probe positions using a .pos file
Added dependence on affyio
MVCClass
Added a slot to the graphView class
oligo
Bugfixes in image and boxplot and normalize.quantiles
Added dependence on affyio
Fixed a bug for affy expression arrays
RMAGEML
Added help file for getSubmitterAddress function
ScISI
Added checkComplex to check protein complexes inclusion within the ScISI and a new data set
Updated the constructScISI file so that it generates datasets and saves them to a directory of choice
Added a vignette that explains the creation of the interactome
Added functions to calculate all graph stats as well as a vignette
sizepower
New Package:
This package has been prepared to assist users in computing either a sample size or power value for a microarray experimental study.
The user is referred to the cited references for technical background on the methodology underpinning these calculations.
This package provides support for five types of sample size and power calculations. These five types can be adapted in various ways to encompass many of the standard designs encountered in practice
Maintainer:
Weiliang Qiu
snapCGH
Changed optimizer from Nelder-Mead from praxis to increase stability of results
Changed plotSegmentedGenome to accept more than one SegList object
Removed code replication with aCGH package
Added arguments to runDNAcopy allowing all the available parameters to be set
Added 'seed' argument to sim.structure to allow reproducible results
Made the default information about chromosome length into megabases rather than base pairs
Removed unneeded argument 'maxiter' from fitBioHMM
Changed plotSegmentedGenome to make chromosomal segments consisting of a single clone more obvious
fitBioHMM now computed the distance between clones automatically
Fixed bug in fitBioHMM where selecting BIC as the criterion caused a crash
SNPscan
New Package:
This package contains methods for visualization of SNP chip data
Maintainer:
Robert Scharpf
xcms
EIC width can now be specified in diffreport
Better error reporting in getEIC