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AffiXcan

This is the development version of AffiXcan; for the stable release version, see AffiXcan.

A Functional Approach To Impute Genetically Regulated Expression


Bioconductor version: Development (3.19)

Impute a GReX (Genetically Regulated Expression) for a set of genes in a sample of individuals, using a method based on the Total Binding Affinity (TBA). Statistical models to impute GReX can be trained with a training dataset where the real total expression values are known.

Author: Alessandro Lussana [aut, cre]

Maintainer: Alessandro Lussana <alessandro.lussana at protonmail.com>

Citation (from within R, enter citation("AffiXcan")):

Installation

To install this package, start R (version "4.4") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("AffiXcan")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

Reference Manual PDF

Details

biocViews DimensionReduction, GeneExpression, GeneRegulation, PrincipalComponent, Regression, Software, Transcription
Version 1.21.0
In Bioconductor since BioC 3.8 (R-3.5) (5.5 years)
License GPL-3
Depends R (>= 3.6), SummarizedExperiment
Imports MultiAssayExperiment, BiocParallel, crayon
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Suggests BiocStyle, knitr, rmarkdown
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package
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Source Repository git clone https://git.bioconductor.org/packages/AffiXcan
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/AffiXcan
Package Short Url https://bioconductor.org/packages/AffiXcan/
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