DESeq

Differential gene expression analysis based on the negative binomial distribution

Bioconductor version: Release (2.9)

Estimate variance-mean dependence in count data from high-throughput sequencing assays and test for differential expression based on a model using the negative binomial distribution

Author: Simon Anders, EMBL Heidelberg

Maintainer: Simon Anders

To install this package, start R and enter:

    source("http:///biocLite.R")
    biocLite("DESeq")

To cite this package in a publication, start R and enter:

    citation("DESeq")

Documentation

PDF R Script Analysing RNA-Seq data with the "DESeq" package
PDF   Reference Manual
Text   NEWS

Details

biocViews HighThroughputSequencing, ChIPseq, RNAseq, SAGE, DifferentialExpression
Depends Biobase, locfit
Imports genefilter, geneplotter, methods, MASS
Suggests pasilla
System Requirements
License GPL (>= 3)
URL http://www-huber.embl.de/users/anders/DESeq
Depends On Me
Imports Me ArrayExpressHTS, DiffBind, EDASeq, rnaSeqMap
Suggests Me DiffBind, EDASeq, GenomicRanges
Version 1.6.1
Since Bioconductor 2.6 (R-2.11)

Package Downloads

Package Source DESeq_1.6.1.tar.gz
Windows Binary DESeq_1.6.1.zip (32- & 64-bit)
MacOS 10.5 (Leopard) binary DESeq_1.6.1.tgz
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