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Disease Ontology Semantic and Enrichment analysis

Bioconductor version: Release (3.0)

This package implements five methods proposed by Resnik, Schlicker, Jiang, Lin and Wang respectively for measuring semantic similarities among DO terms and gene products. Enrichment analyses including hypergeometric model and gene set enrichment analysis are also implemented for discovering disease associations of high-throughput biological data.

Author: Guangchuang Yu, Li-Gen Wang

Maintainer: Guangchuang Yu <guangchuangyu at>

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PDF R Script DOSE - an R package for Disease Ontology Semantic and Enrichment
PDF   Reference Manual
Text   NEWS


biocViews Annotation, GeneSetEnrichment, MultipleComparison, Software, Visualization
Version 2.4.0
In Bioconductor since BioC 2.9 (R-2.14)
License Artistic-2.0
Depends R (>= 3.0.0)
Imports methods, plyr, qvalue, stats4, AnnotationDbi, DO.db, igraph, scales, reshape2, graphics, GOSemSim, grid, ggplot2
Suggests, clusterProfiler, ReactomePA, ChIPseeker, knitr
Depends On Me
Imports Me clusterProfiler, facopy, ReactomePA
Suggests Me ChIPseeker, GOSemSim

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