To install this package, start R and enter:

source("http://bioconductor.org/biocLite.R")
biocLite("birta")

In most cases, you don't need to download the package archive at all.

birta

Bayesian Inference of Regulation of Transcriptional Activity

Bioconductor version: Release (3.0)

Expression levels of mRNA molecules are regulated by different processes, comprising inhibition or activation by transcription factors and post-transcriptional degradation by microRNAs. birta (Bayesian Inference of Regulation of Transcriptional Activity) uses the regulatory networks of TFs and miRNAs together with mRNA and miRNA expression data to predict switches in regulatory activity between two conditions. A Bayesian network is used to model the regulatory structure and Markov-Chain-Monte-Carlo is applied to sample the activity states.

Author: Benedikt Zacher, Khalid Abnaof, Stephan Gade, Erfan Younesi, Achim Tresch, Holger Froehlich

Maintainer: Benedikt Zacher <zacher at lmb.uni-muenchen.de>, Holger Froehlich <frohlich at bit.uni-bonn.de>

Citation (from within R, enter citation("birta")):

Installation

To install this package, start R and enter:

source("http://bioconductor.org/biocLite.R")
biocLite("birta")

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("birta")

 

PDF R Script Bayesian Inference of Regulation of Transcriptional Activity
PDF   Reference Manual
Text   NEWS

Details

biocViews GeneExpression, GraphAndNetwork, Microarray, Sequencing, Software, Transcription
Version 1.10.0
In Bioconductor since BioC 2.10 (R-2.15)
License GPL (>= 2)
Depends limma, MASS, R (>= 2.10), Biobase, methods
Imports
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URL
Depends On Me
Imports Me
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Package Archives

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Package Source birta_1.10.0.tar.gz
Windows Binary birta_1.10.0.zip (32- & 64-bit)
Mac OS X 10.6 (Snow Leopard) birta_1.10.0.tgz
Mac OS X 10.9 (Mavericks) birta_1.10.0.tgz
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