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Analysis of cell-based screens - revised version of cellHTS

Bioconductor version: Release (3.2)

This package provides tools for the analysis of high-throughput assays that were performed in microtitre plate formats (including but not limited to 384-well plates). The functionality includes data import and management, normalisation, quality assessment, replicate summarisation and statistical scoring. A webpage that provides a detailed graphical overview over the data and analysis results is produced. In our work, we have applied the package to RNAi screens on fly and human cells, and for screens of yeast libraries. See ?cellHTS2 for a brief introduction.

Author: Ligia Bras, Wolfgang Huber <whuber at>, Michael Boutros <m.boutros at>, Gregoire Pau <gpau at>, Florian Hahne <florian.hahne at>

Maintainer: Joseph Barry <joseph.barry at>

Citation (from within R, enter citation("cellHTS2")):


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PDF Main vignette (complete version): End-to-end analysis of cell-based screens
PDF Main vignette: End-to-end analysis of cell-based screens
PDF Supplement: enhancer-suppressor screens
PDF Supplement: multi-channel assays
PDF   Reference Manual


biocViews CellBasedAssays, Preprocessing, Software, Visualization
Version 2.34.0
In Bioconductor since BioC 2.1 (R-2.6) (8 years)
License Artistic-2.0
Depends R (>= 2.10), RColorBrewer, Biobase, methods, genefilter, splots, vsn, hwriter, locfit, grid
Imports prada, GSEABase, Category, stats4
Depends On Me coRNAi, imageHTS, staRank
Imports Me gespeR, HTSanalyzeR, RNAinteract
Suggests Me bioassayR
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