Practical DNA Microarray Analysis
Axel
Benner1, Benedikt
Brors2, Anja von
Heydebreck3, Wolfgang Huber4,
Ulrich Mansmann5, Florian
Markowetz3, Jörg
Rahnenführer6, Rainer
Spang3
1 German Cancer Research Center,
Heidelberg, Central Unit Biostatistics;
2 German Cancer
Research Center, Heidelberg, Dep. Intelligent Bioinformatics
Systems;
3 Max-Planck-Institute for Molecular
Genetics, Berlin, Dep. Computational Molecular Biology;
4 German Cancer
Research Center, Heidelberg, Dep. Molecular Genome
Analysis;
5 Univ. of Heidelberg,
Institute for Medical Biometry;
6 Max-Plack-Institute for Informatics,
Saarbrücken.
| Monday | ||
| 09.00-10.30 | First analysis steps | Wolfgang Huber |
| 11.00-12.30 | Differential gene expression | Anja von Heydebreck |
| 13.30-14.30 | First steps in R | Florian Markowetz |
| 14.45-17.00 | Exercises: Exploring cDNA data | Wolfgang Huber |
| Tuesday | ||
| 09.00-10.30 | Exploratory data analysis | Jörg Rahnenführer |
| 10.30-12.00 | Annotation | Benedikt Brors |
| 13.30-14.30 | BioConductor | Wolfgang Huber |
| 14.45-17.00 | Exercises: 2x2 factorial design | Wolfgang Huber |
| Wednesday | ||
| 09.00-10.15 | Molecular Diagnosis | Rainer Spang |
| 10.15-11.00 | Classification by Support Vector Machines | Florian Markowetz |
| 11.00-12.00 | Resampling and the bootstrap | Axel Benner |
| 13.30-17.00 | Exercises: classification | Florian Markowetz |
| Thursday | ||
| 09.00-11.00 | Design of microarray experiments | Ulrich Mansmann |
| 11.00-12.00 | Model Assessment and Selection | Axel Benner |
| 12.00-12.30 | Screening by ROC curve analysis | Axel Benner |
| 13.30-17.00 | Exercises: Model selection, Bootstrap | Ulrich Mansmann Axel Benner |
© Copyright 2003, All rights reserved
Datasets used in the afternoon exercises can be found in the Lab Materials section of www.bioconductor.org.
Course format:
ca. 15 students from laboratories that work with microarrays. In
the mornings, theory lectures; in the afternoons,
hands-on-experience in computer-classes with real data sets (public
data, or students' own data), using R/Bioconductor.
Course dates:
Berlin, Jan 27-30; Heidelberg Mar 24-27; Heidelberg Oct 07-10;
Berlin Nov 10-13.
Course homepage:
at http://compdiag.molgen.mpg.de/ngfn/.
There will be further courses in 2004 which can be found on the
same website.