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Coralysis

This is the released version of Coralysis; for the devel version, see Coralysis.

All versions 3.24 (devel), 3.23 (release), 3.22

Coralysis sensitive identification of imbalanced cell types and states in single-cell data via multi-level integration


Bioconductor version: Release (3.23)

Coralysis is an R package featuring a multi-level integration algorithm for sensitive integration, reference-mapping, and cell-state identification in single-cell data. The multi-level integration algorithm is inspired by the process of assembling a puzzle - where one begins by grouping pieces based on low-to high-level features, such as color and shading, before looking into shape and patterns. This approach progressively blends the batch effects and separates cell types across multiple rounds of divisive clustering.

Author: António Sousa [cre, aut] ORCID iD ORCID: 0000-0003-4779-6459 , Johannes Smolander [ctb, aut] ORCID iD ORCID: 0000-0003-3872-9668 , Sini Junttila [aut] ORCID iD ORCID: 0000-0003-3754-5584 , Laura L Elo [aut] ORCID iD ORCID: 0000-0001-5648-4532

Maintainer: António Sousa <aggode at utu.fi>

Citation (from within R, enter citation("Coralysis")):

António Sousa, Johannes Smolander, Sini Junttila, Laura L Elo. Coralysis: Coralysis sensitive identification of imbalanced cell types and states in single-cell data via multi-level integration. doi:10.18129/B9.bioc.Coralysis, R package version 1.2.0, https://bioconductor.org/packages/Coralysis.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("Coralysis")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("Coralysis")
Cell States HTML R Script
Get started HTML R Script
Integration HTML R Script
Reference-mapping HTML R Script
Reference ManualPDF
NEWSText

Details

biocViews Annotation, BatchEffect, Classification, Clustering, DifferentialExpression, DimensionReduction, GeneExpression, Proteomics, RNASeq, SingleCell, Software, Transcriptomics
Version1.2.0
In Bioconductor sinceBioC 3.22 (R-4.5) (1 year)
License GPL-3
Depends R (>= 4.2.0)
Imports Matrix, aricode, LiblineaR, SparseM, ggplot2, umap, Rtsne, pheatmap, reshape2, dplyr, SingleCellExperiment, SummarizedExperiment, S4Vectors, methods, stats, utils, RANN, sparseMatrixStats, irlba, flexclust, scran, class, matrixStats, tidyr, cowplot, uwot, scatterpie, RColorBrewer, ggrastr, ggrepel, RSpectra, BiocParallel, withr
System Requirements
URLhttps://github.com/elolab/Coralysis https://elolab.github.io/Coralysis/
Bug Reportshttps://github.com/elolab/Coralysis/issues
See More
Suggests knitr, rmarkdown, bluster, ComplexHeatmap, circlize, scater, viridis, scRNAseq, SingleR, MouseGastrulationData, testthat (>= 3.0.0), BiocStyle, scrapper
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package Coralysis_1.2.0.tar.gz
Windows Binary (x86_64) Coralysis_1.2.0.zip
macOS Binary (big-sur-x86_64) Coralysis_1.2.0.tgz
macOS Binary (sonoma-arm64) Coralysis_1.2.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/Coralysis
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/Coralysis
Package Short Url https://bioconductor.org/packages/Coralysis/
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