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HiCDOC

This is the released version of HiCDOC; for the devel version, see HiCDOC.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16

A/B compartment detection and differential analysis


Bioconductor version: Release (3.23)

HiCDOC normalizes intrachromosomal Hi-C matrices, uses unsupervised learning to predict A/B compartments from multiple replicates, and detects significant compartment changes between experiment conditions. It provides a collection of functions assembled into a pipeline to filter and normalize the data, predict the compartments and visualize the results. It accepts several type of data: tabular `.tsv` files, Cooler `.cool` or `.mcool` files, Juicer `.hic` files or HiC-Pro `.matrix` and `.bed` files.

Author: Kurylo Cyril [aut], Zytnicki Matthias [aut], Foissac Sylvain [aut], Maigné Élise [aut, cre]

Maintainer: Maigné Élise <elise.maigne at inrae.fr>

Citation (from within R, enter citation("HiCDOC")):

Kurylo Cyril, Zytnicki Matthias, Foissac Sylvain, Maigné Élise. HiCDOC: A/B compartment detection and differential analysis. doi:10.18129/B9.bioc.HiCDOC, R package version 1.14.0, https://bioconductor.org/packages/HiCDOC.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("HiCDOC")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("HiCDOC")
HiCDOC HTML R Script
Reference ManualPDF
NEWSText

Details

biocViews Clustering, DNA3DStructure, HiC, Normalization, Sequencing, Software
Version1.14.0
In Bioconductor sinceBioC 3.16 (R-4.2) (4 years)
License LGPL-3
Depends InteractionSet, GenomicRanges, SummarizedExperiment, R (>= 4.1.0)
Imports methods, ggplot2, Rcpp (>= 0.12.8), stats, S4Vectors, gtools, pbapply, BiocParallel, BiocGenerics, grid, cowplot, gridExtra, data.table, multiHiCcompare, Seqinfo
System RequirementsC++11
URLhttps://github.com/mzytnicki/HiCDOC
Bug Reportshttps://github.com/mzytnicki/HiCDOC/issues
See More
Suggests knitr, rmarkdown, testthat, BiocStyle, BiocManager, rhdf5
Linking To Rcpp
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package HiCDOC_1.14.0.tar.gz
Windows Binary (x86_64) HiCDOC_1.14.0.zip
macOS Binary (big-sur-x86_64) HiCDOC_1.14.0.tgz
macOS Binary (sonoma-arm64) HiCDOC_1.14.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/HiCDOC
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/HiCDOC
Package Short Url https://bioconductor.org/packages/HiCDOC/
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