Bioconductor Developer Survey 2026 Now Open!

HiLDA

This is the released version of HiLDA; for the devel version, see HiLDA.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13, 3.12, 3.11, 3.10

Conducting statistical inference on comparing the mutational exposures of mutational signatures by using hierarchical latent Dirichlet allocation


Bioconductor version: Release (3.23)

A package built under the Bayesian framework of applying hierarchical latent Dirichlet allocation. It statistically tests whether the mutational exposures of mutational signatures (Shiraishi-model signatures) are different between two groups. The package also provides inference and visualization.

Author: Zhi Yang [aut, cre], Yuichi Shiraishi [ctb]

Maintainer: Zhi Yang <zyang895 at gmail.com>

Citation (from within R, enter citation("HiLDA")):

Zhi Yang. HiLDA: Conducting statistical inference on comparing the mutational exposures of mutational signatures by using hierarchical latent Dirichlet allocation. doi:10.18129/B9.bioc.HiLDA, R package version 1.26.0, https://bioconductor.org/packages/HiLDA.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("HiLDA")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("HiLDA")
An introduction to HiLDA HTML R Script
Reference ManualPDF
NEWSText
INSTALLText

Details

biocViews Bayesian, Sequencing, Software, SomaticMutation, StatisticalMethod
Version1.26.0
In Bioconductor sinceBioC 3.10 (R-3.6) (7 years)
License GPL-3
Depends R (>= 4.1), ggplot2
Imports R2jags, abind, cowplot, grid, forcats, stringr, GenomicRanges, S4Vectors, XVector, Biostrings, GenomicFeatures, BSgenome.Hsapiens.UCSC.hg19, BiocGenerics, tidyr, grDevices, stats, TxDb.Hsapiens.UCSC.hg19.knownGene, utils, methods, Rcpp
System RequirementsJAGS 4.0.0
URLhttps://github.com/USCbiostats/HiLDA https://doi.org/10.1101/577452
Bug Reportshttps://github.com/USCbiostats/HiLDA/issues
See More
Suggests knitr, rmarkdown, testthat, BiocStyle
Linking To Rcpp
Enhances
Depends On Me
Imports Me selectKSigs
Suggests Me
Links To Me
Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package HiLDA_1.26.0.tar.gz
Windows Binary (x86_64) HiLDA_1.26.0.zip (64-bit only)
macOS Binary (big-sur-x86_64) HiLDA_1.26.0.tgz
macOS Binary (sonoma-arm64) HiLDA_1.26.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/HiLDA
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/HiLDA
Package Short Url https://bioconductor.org/packages/HiLDA/
Package Downloads ReportDownload Stats