Bioconductor Developer Survey 2026 Now Open!

STADyUM

This is the released version of STADyUM; for the devel version, see STADyUM.

All versions 3.24 (devel), 3.23 (release), 3.22

Statistical Transcriptome Analysis under a Dynamic Unified Model


Bioconductor version: Release (3.23)

STADyUM is a package with functionality for analyzing nascent RNA read counts to infer transcription rates. This includes utilities for processing experimental nascent RNA read counts as well as for simulating PRO-seq data. Rates such as initiation, pause release and landing pad occupancy are estimated from either synthetic or experimental data. There are also options for varying pause sites and including steric hindrance of initiation in the model.

Author: Yixin Zhao [aut] ORCID iD ORCID: 0000-0002-7856-2818 , Lingjie Liu [aut] ORCID iD ORCID: 0000-0002-5765-1213 , Rebecca Hassett [aut, cre] ORCID iD ORCID: 0000-0001-5133-9387

Maintainer: Rebecca Hassett <hassett at cshl.edu>

Citation (from within R, enter citation("STADyUM")):

Yixin Zhao, Lingjie Liu, Rebecca Hassett. STADyUM: Statistical Transcriptome Analysis under a Dynamic Unified Model. doi:10.18129/B9.bioc.STADyUM, R package version 1.2.0, https://bioconductor.org/packages/STADyUM.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("STADyUM")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("STADyUM")
STADyUM: Simulating and Analyzing Transcription Dynamics HTML R Script
Reference ManualPDF
NEWSText
LICENSEText

Details

biocViews Sequencing, Software, StatisticalMethod, Transcription, Transcriptomics
Version1.2.0
In Bioconductor sinceBioC 3.22 (R-4.5) (1 year)
License MIT + file LICENSE
Depends R (>= 4.5.0)
Imports GenomicRanges, IRanges, S4Vectors, methods, tibble, dplyr, ggplot2, progress, GenomeInfoDb, Rcpp, data.table, purrr, rtracklayer, tidyr, rlang, MASS
System Requirements
URLhttps://github.com/rhassett-cshl/STADyUM
Bug Reportshttps://github.com/rhassett-cshl/STADyUM
See More
Suggests testthat (>= 3.0.0), knitr, rmarkdown, devtools
Linking To Rcpp
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package STADyUM_1.2.0.tar.gz
Windows Binary (x86_64) STADyUM_1.1.3.zip
macOS Binary (big-sur-x86_64) STADyUM_1.2.0.tgz
macOS Binary (sonoma-arm64) STADyUM_1.2.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/STADyUM
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/STADyUM
Package Short Url https://bioconductor.org/packages/STADyUM/
Package Downloads ReportDownload Stats