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airpart

This is the released version of airpart; for the devel version, see airpart.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13

Differential cell-type-specific allelic imbalance


Bioconductor version: Release (3.23)

Airpart identifies sets of genes displaying differential cell-type-specific allelic imbalance across cell types or states, utilizing single-cell allelic counts. It makes use of a generalized fused lasso with binomial observations of allelic counts to partition cell types by their allelic imbalance. Alternatively, a nonparametric method for partitioning cell types is offered. The package includes a number of visualizations and quality control functions for examining single cell allelic imbalance datasets.

Author: Wancen Mu [aut, cre] ORCID iD ORCID: 0000-0002-5061-7581 , Michael Love [aut, ctb] ORCID iD ORCID: 0000-0001-8401-0545

Maintainer: Wancen Mu <wancen at live.unc.edu>

Citation (from within R, enter citation("airpart")):

Wancen Mu, Michael Love. airpart: Differential cell-type-specific allelic imbalance. doi:10.18129/B9.bioc.airpart, R package version 1.20.0, https://bioconductor.org/packages/airpart.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("airpart")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("airpart")
Differential allelic imbalance with airpart HTML R Script
Reference ManualPDF
NEWSText

Details

biocViews ATACSeq, CellBiology, ChIPSeq, Clustering, DifferentialExpression, FunctionalGenomics, GeneExpression, GeneRegulation, GraphAndNetwork, QualityControl, RNASeq, Regression, Sequencing, SingleCell, Software, Transcription, TranscriptomeVariant
Version1.20.0
In Bioconductor sinceBioC 3.13 (R-4.1) (5.5 years)
License GPL-2
Depends R (>= 4.1)
Imports SingleCellExperiment, SummarizedExperiment, S4Vectors, scater, stats, smurf, apeglm (>= 1.13.3), emdbook, mclust, clue, dynamicTreeCut, matrixStats, dplyr, plyr, ggplot2, ComplexHeatmap, forestplot, RColorBrewer, rlang, lpSolve, grid, grDevices, graphics, utils, pbapply
System Requirements
URLhttps://github.com/Wancen/airpart
Bug Reportshttps://github.com/Wancen/airpart/issues
See More
Suggests knitr, rmarkdown, roxygen2 (>= 6.0.0), testthat (>= 3.0.0), gplots, tidyr
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package airpart_1.20.0.tar.gz
Windows Binary (x86_64) airpart_1.20.0.zip
macOS Binary (big-sur-x86_64) airpart_1.20.0.tgz
macOS Binary (sonoma-arm64) airpart_1.20.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/airpart
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/airpart
Package Short Url https://bioconductor.org/packages/airpart/
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