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celda

This is the released version of celda; for the devel version, see celda.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13, 3.12, 3.11, 3.10, 3.9

CEllular Latent Dirichlet Allocation


Bioconductor version: Release (3.23)

Celda is a suite of Bayesian hierarchical models for clustering single-cell RNA-sequencing (scRNA-seq) data. It is able to perform "bi-clustering" and simultaneously cluster genes into gene modules and cells into cell subpopulations. It also contains DecontX, a novel Bayesian method to computationally estimate and remove RNA contamination in individual cells without empty droplet information. A variety of scRNA-seq data visualization functions is also included.

Author: Joshua Campbell [aut, cre], Shiyi Yang [aut], Zhe Wang [aut], Sean Corbett [aut], Yusuke Koga [aut]

Maintainer: Joshua Campbell <camp at bu.edu>

Citation (from within R, enter citation("celda")):

Joshua Campbell, Shiyi Yang, Zhe Wang, Sean Corbett, Yusuke Koga. celda: CEllular Latent Dirichlet Allocation. doi:10.18129/B9.bioc.celda, R package version 1.28.0, https://bioconductor.org/packages/celda.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("celda")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("celda")
Analysis of single-cell genomic data with celda HTML R Script
Estimate and remove cross-contamination from ambient RNA in single-cell data with DecontX HTML R Script
Reference ManualPDF
NEWSText
LICENSEText

Details

biocViews Bayesian, Clustering, DataImport, GeneExpression, ImmunoOncology, Sequencing, SingleCell, Software
Version1.28.0
In Bioconductor sinceBioC 3.9 (R-3.6) (7.5 years)
License MIT + file LICENSE
Depends R (>= 4.0), SingleCellExperiment, Matrix
Imports plyr, foreach, ggplot2, RColorBrewer, grid, scales, gtable, grDevices, graphics, matrixStats, doParallel, digest, methods, reshape2, S4Vectors, data.table, Rcpp, RcppEigen, uwot, enrichR, SummarizedExperiment, MCMCprecision, ggrepel, Rtsne, withr, scater (>= 1.14.4), scran, dbscan, DelayedArray, stringr, ComplexHeatmap, gridExtra, circlize, dendextend, ggdendro, pROC
System Requirements
URL
Bug Reportshttps://github.com/campbio/celda/issues
See More
Suggests testthat, knitr, roxygen2, rmarkdown, biomaRt, covr, BiocManager, BiocStyle, TENxPBMCData, singleCellTK, M3DExampleData
Linking To Rcpp, RcppEigen
Enhances
Depends On Me
Imports Me decontX, singleCellTK
Suggests Me
Links To Me
Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package celda_1.28.0.tar.gz
Windows Binary (x86_64) celda_1.28.0.zip
macOS Binary (big-sur-x86_64) celda_1.28.0.tgz
macOS Binary (sonoma-arm64) celda_1.28.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/celda
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/celda
Package Short Url https://bioconductor.org/packages/celda/
Package Downloads ReportDownload Stats