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cfDNAPro

This is the released version of cfDNAPro; for the devel version, see cfDNAPro.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.12

cfDNAPro extracts and Visualises biological features from whole genome sequencing data of cell-free DNA


Bioconductor version: Release (3.23)

cfDNA fragments carry important features for building cancer sample classification ML models, such as fragment size, and fragment end motif etc. Analyzing and visualizing fragment size metrics, as well as other biological features in a curated, standardized, scalable, well-documented, and reproducible way might be time intensive. This package intends to resolve these problems and simplify the process. It offers two sets of functions for cfDNA feature characterization and visualization.

Author: Haichao Wang [aut, cre], Hui Zhao [ctb], Elkie Chan [ctb], Christopher Smith [ctb], Tomer Kaplan [ctb], Florian Markowetz [ctb], Nitzan Rosenfeld [ctb]

Maintainer: Haichao Wang <hw538 at cam.ac.uk>

Citation (from within R, enter citation("cfDNAPro")):

Haichao Wang. cfDNAPro: cfDNAPro extracts and Visualises biological features from whole genome sequencing data of cell-free DNA. doi:10.18129/B9.bioc.cfDNAPro, R package version 1.18.0, https://bioconductor.org/packages/cfDNAPro.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("cfDNAPro")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("cfDNAPro")
cfDNAPro Tutorial HTML R Script
Reference ManualPDF
NEWSText

Details

biocViews Sequencing, Software, Visualization, WholeGenome
Version1.18.0
In Bioconductor sinceBioC 3.12 (R-4.0) (6 years)
License GPL-3
Depends R (>= 4.1.0), magrittr (>= 1.5.0)
Imports tibble, GenomicAlignments, IRanges, plyranges, GenomeInfoDb, GenomicRanges, BiocGenerics, stats, utils, dplyr (>= 0.8.3), stringr (>= 1.4.0), quantmod (>= 0.4), ggplot2 (>= 3.2.1), Rsamtools (>= 2.4.0), rlang (>= 0.4.0), BSgenome.Hsapiens.UCSC.hg38, BSgenome.Hsapiens.UCSC.hg19, BSgenome.Hsapiens.NCBI.GRCh38
System Requirements
URLhttps://github.com/hw538/cfDNAPro
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Suggests scales, ggpubr, knitr (>= 1.23), rmarkdown (>= 1.14), devtools (>= 2.3.0), BiocStyle, testthat
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package cfDNAPro_1.18.0.tar.gz
Windows Binary (x86_64) cfDNAPro_1.18.0.zip
macOS Binary (big-sur-x86_64) cfDNAPro_1.18.0.tgz
macOS Binary (sonoma-arm64) cfDNAPro_1.18.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/cfDNAPro
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/cfDNAPro
Package Short Url https://bioconductor.org/packages/cfDNAPro/
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