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cleanUpdTSeq

This is the released version of cleanUpdTSeq; for the devel version, see cleanUpdTSeq.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13, 3.12, 3.11, 3.10, 3.9, 3.8, 3.7, 3.6, 3.5, 3.4, 3.3, 3.2, 3.1, 3.0, 2.14, 2.13

cleanUpdTSeq cleans up artifacts from polyadenylation sites from oligo(dT)-mediated 3' end RNA sequending data


Bioconductor version: Release (3.23)

This package implements a Naive Bayes classifier for accurately differentiating true polyadenylation sites (pA sites) from oligo(dT)-mediated 3' end sequencing such as PAS-Seq, PolyA-Seq and RNA-Seq by filtering out false polyadenylation sites, mainly due to oligo(dT)-mediated internal priming during reverse transcription. The classifer is highly accurate and outperforms other heuristic methods.

Author: Sarah Sheppard, Haibo Liu, Jianhong Ou, Nathan Lawson, Lihua Julie Zhu

Maintainer: Jianhong Ou <jou at morgridge.org>; Lihua Julie Zhu <Julie.Zhu at umassmed.edu>

Citation (from within R, enter citation("cleanUpdTSeq")):

Sarah Sheppard, Haibo Liu, Jianhong Ou, Nathan Lawson, Lihua Julie Zhu. cleanUpdTSeq: cleanUpdTSeq cleans up artifacts from polyadenylation sites from oligo(dT)-mediated 3' end RNA sequending data. doi:10.18129/B9.bioc.cleanUpdTSeq, R package version 1.50.0, https://bioconductor.org/packages/cleanUpdTSeq.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("cleanUpdTSeq")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("cleanUpdTSeq")
cleanUpdTSeq Vignette HTML R Script
Reference ManualPDF
NEWSText

Details

biocViews 3' end sequencing, Sequencing, Software, internal priming, polyadenylation site
Version1.50.0
In Bioconductor sinceBioC 2.13 (R-3.0) (13 years)
License GPL-2
Depends R (>= 3.5.0), BSgenome.Drerio.UCSC.danRer7, methods
Imports BSgenome, GenomicRanges, seqinr, e1071, Biostrings, Seqinfo, IRanges, utils, stringr, stats, S4Vectors
System Requirements
URL
See More
Suggests BiocStyle, rmarkdown, knitr, RUnit, BiocGenerics (>= 0.1.0)
Linking To
Enhances
Depends On Me
Imports Me InPAS
Suggests Me
Links To Me
Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package cleanUpdTSeq_1.50.0.tar.gz
Windows Binary (x86_64) cleanUpdTSeq_1.50.0.zip (64-bit only)
macOS Binary (big-sur-x86_64) cleanUpdTSeq_1.50.0.tgz
macOS Binary (sonoma-arm64) cleanUpdTSeq_1.50.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/cleanUpdTSeq
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/cleanUpdTSeq
Package Short Url https://bioconductor.org/packages/cleanUpdTSeq/
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