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demuxmix

This is the released version of demuxmix; for the devel version, see demuxmix.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16

Demultiplexing oligo-barcoded scRNA-seq data using regression mixture models


Bioconductor version: Release (3.23)

A package for demultiplexing single-cell sequencing experiments of pooled cells labeled with barcode oligonucleotides. The package implements methods to fit regression mixture models for a probabilistic classification of cells, including multiplet detection. Demultiplexing error rates can be estimated, and methods for quality control are provided.

Author: Hans-Ulrich Klein [aut, cre] ORCID iD ORCID: 0000-0002-6382-9428

Maintainer: Hans-Ulrich Klein <hansulrich.klein at gmail.com>

Citation (from within R, enter citation("demuxmix")):

Hans-Ulrich Klein. demuxmix: Demultiplexing oligo-barcoded scRNA-seq data using regression mixture models. doi:10.18129/B9.bioc.demuxmix, R package version 1.14.0, https://bioconductor.org/packages/demuxmix.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("demuxmix")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("demuxmix")
Demultiplexing cells with demuxmix HTML R Script
Reference ManualPDF
NEWSText

Details

biocViews Classification, Preprocessing, Regression, Sequencing, SingleCell, Software
Version1.14.0
In Bioconductor sinceBioC 3.16 (R-4.2) (4 years)
License Artistic-2.0
Depends R (>= 4.0.0)
Imports stats, MASS, Matrix, ggplot2, gridExtra, methods
System Requirements
URLhttps://github.com/huklein/demuxmix
Bug Reportshttps://github.com/huklein/demuxmix/issues
See More
Suggests BiocStyle, cowplot, DropletUtils, knitr, reshape2, rmarkdown, testthat (>= 3.0.0)
Linking To
Enhances
Depends On Me
Imports Me demuxSNP
Suggests Me
Links To Me
Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package demuxmix_1.14.0.tar.gz
Windows Binary (x86_64) demuxmix_1.14.0.zip
macOS Binary (big-sur-x86_64) demuxmix_1.14.0.tgz
macOS Binary (sonoma-arm64) demuxmix_1.14.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/demuxmix
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/demuxmix
Package Short Url https://bioconductor.org/packages/demuxmix/
Package Downloads ReportDownload Stats