Bioconductor Developer Survey 2026 Now Open!

HiSpaR

Hierarchical Inference of Spatial Positions from Hi-C Data

Bioconductor version: 3.24 · Package version: 1.1.0

Other Bioconductor versions

devel is the development version; release is the current stable one.

3.24 (devel), 3.23 (release)

Provides R bindings for HiSpa, a hierarchical Bayesian model for inferring three-dimensional chromatin structures from Hi-C contact matrices using Markov Chain Monte Carlo (MCMC) sampling. The package implements a cluster-based hierarchical approach that efficiently handles large-scale Hi-C datasets. It uses Rcpp and RcppArmadillo for efficient C++ integration with the original HiSpa C++ implementation, enabling fast computation of chromatin structure inference through parallel MCMC sampling.

DOI: 10.18129/B9.bioc.HiSpaR

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("HiSpaR")

Details

MaintainerYingcheng Luo <lyc22@mails.tsinghua.edu.cn>
AuthorYingcheng Luo [aut, cre]
LicenseMIT + file LICENSE
URLhttps://github.com/masterStormtrooper/HiSpaR
Bug Reportshttps://github.com/masterStormtrooper/HiSpaR/issues
System RequirementsC++17, GNU make, Armadillo (>= 9.0), OpenMP
Source branchdevel
Build report Bioconductor build system, r-universe
biocViewsBayesian, Epigenetics, HiC, Software, Spatial, StructuralPrediction
Package Short Url https://bioconductor.org/packages/HiSpaR/

Citation

From within R, enter citation("HiSpaR"):

Yingcheng Luo. HiSpaR: Hierarchical Inference of Spatial Positions from Hi-C Data. doi:10.18129/B9.bioc.HiSpaR, R package version 1.1.0, https://bioconductor.org/packages/HiSpaR.

Generated from the package metadata; it may differ from the package's own citation.

Download

Follow the installation instructions to use this package in your R session.

Source packageHiSpaR_1.1.0.tar.gz
macOS binary (arm64)HiSpaR_1.1.0.tgz
macOS binary (x86_64)HiSpaR_1.1.0.tgz
Dependencies

Depends: R (>= 4.5.0)

Imports: Rcpp (>= 1.0.0), utils, stats, Matrix, HiCExperiment

LinkingTo: Rcpp, RcppArmadillo

Suggests: testthat (>= 3.0.0), knitr, rmarkdown, BiocStyle, rgl, HiContactsData, HiContacts, plotly, callr