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SpatialArtifacts

Identification and Classification of Spatial Artifacts in Visium and Visium HD Data

Bioconductor version: 3.24 · Package version: 1.1.0

Other Bioconductor versions

devel is the development version; release is the current stable one.

3.24 (devel), 3.23 (release)

SpatialArtifacts provides a data-driven two-step workflow to identify, classify, and handle spatial artifacts in spatial transcriptomics data. The package combines median absolute deviation (MAD)-based outlier detection with morphological image processing (fill, outline, and star patterns) to detect edge and interior artifacts. It supports multiple platforms including 10x Genomics Visium (standard and HD), allowing for consistent quality control across different spatial resolutions.

DOI: 10.18129/B9.bioc.SpatialArtifacts

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("SpatialArtifacts")

Details

MaintainerHarriet Jiali He <jhe46@jh.edu>
AuthorHarriet Jiali He [aut, cre] (ORCID: <https://orcid.org/0009-0003-7827-2735>), Jacqueline R. Thompson [aut], Michael Totty [aut], Stephanie C. Hicks [aut, fnd] (ORCID: <https://orcid.org/0000-0002-7858-0231>)
LicenseArtistic-2.0
URLhttps://github.com/CambridgeCat13/SpatialArtifacts
Bug Reportshttps://github.com/CambridgeCat13/SpatialArtifacts/issues
System Requirementsquarto, GDAL (>= 2.0.1), GEOS (>= 3.4.0), PROJ (>= 4.8.0)
Source branchdevel
Build report Bioconductor build system, r-universe
biocViewsClassification, DataImport, QualityControl, Software, Spatial, Transcriptomics, WorkflowStep
Package Short Url https://bioconductor.org/packages/SpatialArtifacts/

Citation

From within R, enter citation("SpatialArtifacts"):

Harriet Jiali He, Jacqueline R. Thompson, Michael Totty, Stephanie C. Hicks. SpatialArtifacts: Identification and Classification of Spatial Artifacts in Visium and Visium HD Data. doi:10.18129/B9.bioc.SpatialArtifacts, R package version 1.1.0, https://bioconductor.org/packages/SpatialArtifacts.

Generated from the package metadata; it may differ from the package's own citation.

Documentation

Download

Follow the installation instructions to use this package in your R session.

Source packageSpatialArtifacts_1.1.0.tar.gz
Windows binary (x86_64)SpatialArtifacts_1.1.0.zip
macOS binary (arm64)SpatialArtifacts_1.1.0.tgz
macOS binary (x86_64)SpatialArtifacts_1.1.0.tgz
Dependencies

Depends: R (>= 4.4.0)

Imports: SpatialExperiment, SummarizedExperiment, S4Vectors, scuttle, dplyr, terra, stats, methods

Suggests: BiocStyle, knitr, rmarkdown, BiocCheck, ggplot2, patchwork, testthat (>= 3.0.0)