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This is the development version of Trendy; for the stable release version, see Trendy.

Breakpoint analysis of time-course expression data

Bioconductor version: Development (3.20)

Trendy implements segmented (or breakpoint) regression models to estimate breakpoints which represent changes in expression for each feature/gene in high throughput data with ordered conditions.

Author: Rhonda Bacher and Ning Leng

Maintainer: Rhonda Bacher <rbacher at>

Citation (from within R, enter citation("Trendy")):


To install this package, start R (version "4.4") and enter:

if (!require("BiocManager", quietly = TRUE))

# The following initializes usage of Bioc devel


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:

Trendy Vignette PDF R Script
Reference Manual PDF


biocViews ImmunoOncology, RNASeq, Regression, Software, TimeCourse
Version 1.27.0
In Bioconductor since BioC 3.7 (R-3.5) (6 years)
License GPL-3
Depends R (>= 3.4)
Imports stats, utils, graphics, grDevices, segmented, gplots, parallel, magrittr, BiocParallel, DT, S4Vectors, SummarizedExperiment, methods, shiny, shinyFiles
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Suggests BiocStyle, knitr, rmarkdown, devtools
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Follow Installation instructions to use this package in your R session.

Source Package Trendy_1.27.0.tar.gz
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macOS Binary (x86_64) Trendy_1.27.0.tgz
macOS Binary (arm64) Trendy_1.27.0.tgz
Source Repository git clone
Source Repository (Developer Access) git clone
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