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diffHic

This is the development version of diffHic; for the stable release version, see diffHic.

All Bioconductor versions of diffHic

3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13, 3.12, 3.11, 3.10, 3.9, 3.8, 3.7, 3.6, 3.5, 3.4, 3.3, 3.2, 3.1

Differential Analysis of Hi-C Data

Bioconductor version: 3.24 · Package version: 1.45.0

Detects differential interactions across biological conditions in a Hi-C experiment. Methods are provided for read alignment and data pre-processing into interaction counts. Statistical analysis is based on edgeR and supports normalization and filtering. Several visualization options are also available.

Author: Aaron Lun, Gordon Smyth

Maintainer: Aaron Lun <infinite.monkeys.with.keyboards at gmail.com>, Gordon Smyth <smyth at wehi.edu.au>, Hannah Coughlin <coughlin.h at wehi.edu.au>

DOI: 10.18129/B9.bioc.diffHic

Citation

From within R, enter citation("diffHic"):

Aaron Lun, Gordon Smyth. diffHic: Differential Analysis of Hi-C Data. doi:10.18129/B9.bioc.diffHic, R package version 1.45.0, https://bioconductor.org/packages/diffHic.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("diffHic")

For older versions of R, please refer to the appropriate Bioconductor release.

Details

Version1.45.0
LicenseGPL-3
System RequirementsC++, GNU make
Last updated2026-04-28
In Bioconductor sinceBioC 3.1 (R-3.2) (11 years)
Downloads rank444 of 2,456
Source branchdevel
Build report Bioconductor build system, r-universe
biocViewsAlignment, Clustering, Coverage, HiC, MultipleComparison, Normalization, Preprocessing, Sequencing, Software
Package Short Url https://bioconductor.org/packages/diffHic/

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("diffHic")
diffHic Vignette PDF
Reference ManualPDF
NEWSText

Download

Follow the installation instructions to use this package in your R session.

Source packagediffHic_1.45.0.tar.gz
Windows binary (x86_64)diffHic_1.45.0.zip
macOS binary (arm64)diffHic_1.45.0.tgz
macOS binary (x86_64)diffHic_1.45.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/diffHic
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/diffHic
Package Downloads ReportDownload Stats
Dependencies

Depends: R (>= 3.5), GenomicRanges, InteractionSet, SummarizedExperiment

Imports: Rsamtools, Rhtslib, Biostrings, BSgenome, rhdf5, edgeR, limma, csaw, locfit, methods, IRanges, S4Vectors, GenomeInfoDb, BiocGenerics, grDevices, graphics, stats, utils, Rcpp, rtracklayer

LinkingTo: Rhtslib (>= 1.13.1), Rcpp

Suggests: BSgenome.Ecoli.NCBI.20080805, Matrix, testthat

Reverse dependencies

Imports Me (1): hicream