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diffHic

Differential Analysis of Hi-C Data

Bioconductor version: 3.23 · Package version: 1.44.0

Other Bioconductor versions

devel is the development version; release is the current stable one.

3.24 (devel), 3.23 (release)

Detects differential interactions across biological conditions in a Hi-C experiment. Methods are provided for read alignment and data pre-processing into interaction counts. Statistical analysis is based on edgeR and supports normalization and filtering. Several visualization options are also available.

DOI: 10.18129/B9.bioc.diffHic

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("diffHic")

Details

MaintainerAaron Lun <infinite.monkeys.with.keyboards@gmail.com>, Gordon Smyth <smyth@wehi.edu.au>, Hannah Coughlin <coughlin.h@wehi.edu.au>
AuthorAaron Lun, Gordon Smyth
LicenseGPL-3
System RequirementsC++, GNU make
Source branchRELEASE_3_23
Build report Bioconductor build system, r-universe
biocViewsAlignment, Clustering, Coverage, HiC, MultipleComparison, Normalization, Preprocessing, Sequencing, Software
Package Short Url https://bioconductor.org/packages/diffHic/

Citation

From within R, enter citation("diffHic"):

Aaron Lun, Gordon Smyth. diffHic: Differential Analysis of Hi-C Data. doi:10.18129/B9.bioc.diffHic, R package version 1.44.0, https://bioconductor.org/packages/diffHic.

Generated from the package metadata; it may differ from the package's own citation.

Documentation

Download

Follow the installation instructions to use this package in your R session.

Source packagediffHic_1.44.0.tar.gz
Windows binary (x86_64)diffHic_1.44.0.zip
macOS binary (arm64)diffHic_1.44.0.tgz
macOS binary (x86_64)diffHic_1.44.0.tgz
Dependencies

Depends: R (>= 3.5), GenomicRanges, InteractionSet, SummarizedExperiment

Imports: Rsamtools, Rhtslib, Biostrings, BSgenome, rhdf5, edgeR, limma, csaw, locfit, methods, IRanges, S4Vectors, GenomeInfoDb, BiocGenerics, grDevices, graphics, stats, utils, Rcpp, rtracklayer

LinkingTo: Rhtslib (>= 1.13.1), Rcpp

Suggests: BSgenome.Ecoli.NCBI.20080805, Matrix, testthat

Reverse dependencies

Imports Me (1): hicream