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enhancerHomologSearch

This is the released version of enhancerHomologSearch; for the devel version, see enhancerHomologSearch.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14

Identification of putative mammalian orthologs to given enhancer


Bioconductor version: Release (3.23)

Get ENCODE data of enhancer region via H3K4me1 peaks and search homolog regions for given sequences. The candidates of enhancer homolog regions can be filtered by distance to target TSS. The top candidates from human and mouse will be aligned to each other and then exported as multiple alignments with given enhancer.

Author: Jianhong Ou [aut, cre] ORCID iD ORCID: 0000-0002-8652-2488 , Valentina Cigliola [dtc], Kenneth Poss [fnd]

Maintainer: Jianhong Ou <jou at morgridge.org>

Citation (from within R, enter citation("enhancerHomologSearch")):

Jianhong Ou. enhancerHomologSearch: Identification of putative mammalian orthologs to given enhancer. doi:10.18129/B9.bioc.enhancerHomologSearch, R package version 1.18.0, https://bioconductor.org/packages/enhancerHomologSearch.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("enhancerHomologSearch")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("enhancerHomologSearch")
enhancerHomologSearch Vignette HTML R Script
Reference ManualPDF
NEWSText

Details

biocViews Alignment, GeneRegulation, Sequencing, Software
Version1.18.0
In Bioconductor sinceBioC 3.14 (R-4.1) (5 years)
License GPL (>= 2)
Depends R (>= 4.1.0), methods
Imports BiocGenerics, Biostrings, BSgenome, BiocParallel, BiocFileCache, Seqinfo, GenomicRanges, httr, IRanges, jsonlite, motifmatchr, Matrix, pwalign, rtracklayer, Rcpp, S4Vectors, stats, utils
System Requirements
URLhttps://jianhong.github.io/enhancerHomologSearch
Bug Reportshttps://github.com/jianhong/enhancerHomologSearch/issues
See More
Suggests GenomeInfoDb, knitr, rmarkdown, BSgenome.Drerio.UCSC.danRer10, BSgenome.Hsapiens.UCSC.hg38, BSgenome.Mmusculus.UCSC.mm10, TxDb.Hsapiens.UCSC.hg38.knownGene, org.Hs.eg.db, TxDb.Mmusculus.UCSC.mm10.knownGene, org.Mm.eg.db, MotifDb, testthat, TFBSTools
Linking To Rcpp
Enhances
Depends On Me
Imports Me
Suggests Me
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Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package enhancerHomologSearch_1.18.0.tar.gz
Windows Binary (x86_64) enhancerHomologSearch_1.18.0.zip
macOS Binary (big-sur-x86_64) enhancerHomologSearch_1.18.0.tgz
macOS Binary (sonoma-arm64) enhancerHomologSearch_1.18.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/enhancerHomologSearch
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/enhancerHomologSearch
Package Short Url https://bioconductor.org/packages/enhancerHomologSearch/
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