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humanHippocampus2024

This is the released version of humanHippocampus2024; for the devel version, see humanHippocampus2024.

Access to SRT and snRNA-seq data from spatial_HPC project


Bioconductor version: Release (3.23)

This is an ExperimentHub Data package that helps to access the spatially-resolved transcriptomics and single-nucleus RNA sequencing data. The datasets are generated from adjacent tissue sections of the anterior human hippocampus across ten adult neurotypical donors. The datasets are based on [spatial_hpc](https://github.com/LieberInstitute/spatial_hpc) project by Lieber Institute for Brain Development (LIBD) researchers and collaborators.

Author: Christine Hou [aut, cre] ORCID iD ORCID: 0009-0001-5350-0629

Maintainer: Christine Hou <chris2018hou at gmail.com>

Citation (from within R, enter citation("humanHippocampus2024")):
Seminal Bioconductor project articles:

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M (2015). "Orchestrating high-throughput genomic analysis with Bioconductor." Nature Methods, 12(2), 115–121. doi:10.1038/nmeth.3252.

Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JYH, Zhang J (2004). "Bioconductor: open software development for computational biology and bioinformatics." Genome Biology, 5(10), R80. doi:10.1186/gb-2004-5-10-r80.

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("humanHippocampus2024")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("humanHippocampus2024")
humanHippocampus2024 Tutorial HTML R Script
Reference Manual PDF
NEWS Text

Details

biocViews ExperimentData, ExperimentHub, ExpressionData, RNASeqData, SequencingData, SpatialData, Tissue
Version 1.4.0
License Artistic-2.0
Depends R (>= 4.4)
Imports ExperimentHub, SummarizedExperiment, SpatialExperiment
System Requirements
URL https://github.com/LieberInstitute/spatial_hpc https://christinehou11.github.io/humanHippocampus2024/
Bug Reports https://support.bioconductor.org/t/humanHippocampus2024
See More
Suggests testthat (>= 3.0.0), sessioninfo, rmarkdown, knitr, BiocStyle, ExperimentHubData, AnnotationHubData, RefManageR
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package humanHippocampus2024_1.4.0.tar.gz
Windows Binary (x86_64)
macOS Binary (big-sur-x86_64)
macOS Binary (sonoma-arm64)
Source Repository git clone https://git.bioconductor.org/packages/humanHippocampus2024
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/humanHippocampus2024
Package Short Url https://bioconductor.org/packages/humanHippocampus2024/
Package Downloads Report Download Stats