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katdetectr

This is the released version of katdetectr; for the devel version, see katdetectr.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16

Detection, Characterization and Visualization of Kataegis in Sequencing Data


Bioconductor version: Release (3.23)

Kataegis refers to the occurrence of regional hypermutation and is a phenomenon observed in a wide range of malignancies. Using changepoint detection katdetectr aims to identify putative kataegis foci from common data-formats housing genomic variants. Katdetectr has shown to be a robust package for the detection, characterization and visualization of kataegis.

Author: Daan Hazelaar [aut, cre] ORCID iD ORCID: 0000-0002-7513-6813 , Job van Riet [aut] ORCID iD ORCID: 0000-0001-7767-7923 , Harmen van de Werken [ths] ORCID iD ORCID: 0000-0002-9794-1477

Maintainer: Daan Hazelaar <daanhazelaar at gmail.com>

Citation (from within R, enter citation("katdetectr")):

Daan Hazelaar, Job van Riet. katdetectr: Detection, Characterization and Visualization of Kataegis in Sequencing Data. doi:10.18129/B9.bioc.katdetectr, R package version 1.14.0, https://bioconductor.org/packages/katdetectr.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("katdetectr")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("katdetectr")
Overview_katdetectr HTML R Script
Reference ManualPDF
NEWSText
LICENSEText

Details

biocViews Classification, SNP, Sequencing, Software, VariantAnnotation, WholeGenome
Version1.14.0
In Bioconductor sinceBioC 3.16 (R-4.2) (4 years)
License GPL-3 + file LICENSE
Depends R (>= 4.2)
Imports Biobase (>= 2.54.0), BiocParallel (>= 1.26.2), BSgenome (>= 1.62.0), BSgenome.Hsapiens.UCSC.hg19 (>= 1.4.3), BSgenome.Hsapiens.UCSC.hg38 (>= 1.4.4), changepoint (>= 2.2.3), changepoint.np (>= 1.0.3), checkmate (>= 2.0.0), dplyr (>= 1.0.8), GenomeInfoDb (>= 1.28.4), GenomicRanges (>= 1.44.0), ggplot2 (>= 3.3.5), ggtext (>= 0.1.1), IRanges (>= 2.26.0), maftools (>= 2.10.5), methods (>= 4.1.3), plyranges (>= 1.17.0), Rdpack (>= 2.3.1), rlang (>= 1.0.2), S4Vectors (>= 0.30.2), scales (>= 1.2.0), tibble (>= 3.1.6), tidyr (>= 1.2.0), tools, utils, VariantAnnotation (>= 1.38.0)
System Requirements
URLhttps://doi.org/doi:10.18129/B9.bioc.katdetectr
Bug Reportshttps://github.com/ErasmusMC-CCBC/katdetectr/issues
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Suggests BiocStyle (>= 2.26.0), knitr (>= 1.37), rmarkdown (>= 2.13), stats, testthat (>= 3.0.0)
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package katdetectr_1.14.0.tar.gz
Windows Binary (x86_64) katdetectr_1.14.0.zip
macOS Binary (big-sur-x86_64) katdetectr_1.14.0.tgz
macOS Binary (sonoma-arm64) katdetectr_1.14.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/katdetectr
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/katdetectr
Package Short Url https://bioconductor.org/packages/katdetectr/
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