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mistyR

This is the released version of mistyR; for the devel version, see mistyR.

All Bioconductor versions of mistyR

3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13

Multiview Intercellular SpaTial modeling framework

Bioconductor version: 3.23 · Package version: 1.20.0

mistyR is an implementation of the Multiview Intercellular SpaTialmodeling framework (MISTy). MISTy is an explainable machine learning framework for knowledge extraction and analysis of single-cell, highly multiplexed, spatially resolved data. MISTy facilitates an in-depth understanding of marker interactions by profiling the intra- and intercellular relationships. MISTy is a flexible framework able to process a custom number of views. Each of these views can describe a different spatial context, i.e., define a relationship among the observed expressions of the markers, such as intracellular regulation or paracrine regulation, but also, the views can also capture cell-type specific relationships, capture relations between functional footprints or focus on relations between different anatomical regions. Each MISTy view is considered as a potential source of variability in the measured marker expressions. Each MISTy view is then analyzed for its contribution to the total expression of each marker and is explained in terms of the interactions with other measurements that led to the observed contribution.

Author: Jovan Tanevski [cre, aut] ORCID iD ORCID: 0000-0001-7177-1003 , Ricardo Omar Ramirez Flores [ctb] ORCID iD ORCID: 0000-0003-0087-371X , Philipp Schäfer [ctb]

Maintainer: Jovan Tanevski <jovan.tanevski at uni-heidelberg.de>

DOI: 10.18129/B9.bioc.mistyR

Citation

From within R, enter citation("mistyR"):

Jovan Tanevski. mistyR: Multiview Intercellular SpaTial modeling framework. doi:10.18129/B9.bioc.mistyR, R package version 1.20.0, https://bioconductor.org/packages/mistyR.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("mistyR")

For older versions of R, please refer to the appropriate Bioconductor release.

Details

Version1.20.0
LicenseGPL-3
URLhttps://saezlab.github.io/mistyR/
Bug Reportshttps://github.com/saezlab/mistyR/issues
Last updated2026-04-28
In Bioconductor sinceBioC 3.13 (R-4.1) (5 years)
Downloads rank1461 of 2,418
Source branchRELEASE_3_23
Build report Bioconductor build system, r-universe
biocViewsBiomedicalInformatics, CellBiology, DecisionTree, Regression, SingleCell, Software, Spatial, SystemsBiology
Package Short Url https://bioconductor.org/packages/mistyR/

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("mistyR")
Modeling spatially resolved omics with mistyR HTML R Script
Reference ManualPDF
NEWSText

Download

Follow the installation instructions to use this package in your R session.

Source packagemistyR_1.20.0.tar.gz
Windows binary (x86_64)mistyR_1.20.0.zip
macOS binary (x86_64)mistyR_1.20.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/mistyR
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/mistyR
Package Downloads ReportDownload Stats
Dependencies

Depends: R (>= 4.0)

Imports: assertthat, caret, deldir, digest, distances, dplyr (>= 1.1.0), filelock, furrr (>= 0.2.0), ggplot2, methods, purrr, ranger, readr (>= 2.0.0), ridge, rlang, rlist, R.utils, stats, stringr, tibble, tidyr, tidyselect (>= 1.2.0), utils, withr

Suggests: BiocStyle, covr, earth, future, igraph (>= 1.2.7), iml, kernlab, knitr, MASS, rmarkdown, RSNNS, testthat (>= 3.0.0), xgboost