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nempi

This is the released version of nempi; for the devel version, see nempi.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13

Inferring unobserved perturbations from gene expression data


Bioconductor version: Release (3.23)

Takes as input an incomplete perturbation profile and differential gene expression in log odds and infers unobserved perturbations and augments observed ones. The inference is done by iteratively inferring a network from the perturbations and inferring perturbations from the network. The network inference is done by Nested Effects Models.

Author: Martin Pirkl [aut, cre]

Maintainer: Martin Pirkl <martinpirkl at yahoo.de>

Citation (from within R, enter citation("nempi")):

Martin Pirkl. nempi: Inferring unobserved perturbations from gene expression data. doi:10.18129/B9.bioc.nempi, R package version 1.20.0, https://bioconductor.org/packages/nempi.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("nempi")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("nempi")
nempi HTML R Script
Reference ManualPDF
NEWSText

Details

biocViews ATACSeq, CRISPR, Classification, DNASeq, DifferentialExpression, DifferentialMethylation, GeneExpression, GeneSignaling, Network, NetworkInference, NeuralNetwork, Pathways, PooledScreens, RNASeq, SingleCell, Software, SystemsBiology
Version1.20.0
In Bioconductor sinceBioC 3.13 (R-4.1) (5.5 years)
License GPL-3
Depends R (>= 4.1), mnem
Imports e1071, nnet, randomForest, naturalsort, graphics, stats, utils, matrixStats, epiNEM
System Requirements
URLhttps://github.com/cbg-ethz/nempi/
Bug Reportshttps://github.com/cbg-ethz/nempi/issues
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Suggests knitr, BiocGenerics, rmarkdown, RUnit, BiocStyle
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Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package nempi_1.20.0.tar.gz
Windows Binary (x86_64) nempi_1.20.0.zip (64-bit only)
macOS Binary (big-sur-x86_64) nempi_1.20.0.tgz
macOS Binary (sonoma-arm64) nempi_1.20.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/nempi
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/nempi
Package Short Url https://bioconductor.org/packages/nempi/
Package Downloads ReportDownload Stats