Bioconductor Developer Survey 2026 Now Open!

proDA

This is the released version of proDA; for the devel version, see proDA.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13, 3.12, 3.11, 3.10

Differential Abundance Analysis of Label-Free Mass Spectrometry Data


Bioconductor version: Release (3.23)

Account for missing values in label-free mass spectrometry data without imputation. The package implements a probabilistic dropout model that ensures that the information from observed and missing values are properly combined. It adds empirical Bayesian priors to increase power to detect differentially abundant proteins.

Author: Constantin Ahlmann-Eltze [aut, cre] ORCID iD ORCID: 0000-0002-3762-068X , Simon Anders [ths] ORCID iD ORCID: 0000-0003-4868-1805

Maintainer: Constantin Ahlmann-Eltze <artjom31415 at googlemail.com>

Citation (from within R, enter citation("proDA")):

Constantin Ahlmann-Eltze. proDA: Differential Abundance Analysis of Label-Free Mass Spectrometry Data. doi:10.18129/B9.bioc.proDA, R package version 1.26.0, https://bioconductor.org/packages/proDA.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("proDA")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("proDA")
Data Import HTML R Script
Introduction HTML R Script
Reference ManualPDF
NEWSText

Details

biocViews Bayesian, DifferentialExpression, MassSpectrometry, Normalization, Proteomics, QualityControl, Regression, Software
Version1.26.0
In Bioconductor sinceBioC 3.10 (R-3.6) (7 years)
License GPL-3
Depends
Imports stats, utils, methods, BiocGenerics, SummarizedExperiment, S4Vectors, extraDistr
System Requirements
URLhttps://github.com/const-ae/proDA
Bug Reportshttps://github.com/const-ae/proDA/issues
See More
Suggests testthat (>= 2.1.0), MSnbase, dplyr, stringr, readr, tidyr, tibble, limma, numDeriv, pheatmap, knitr, rmarkdown, BiocStyle
Linking To
Enhances
Depends On Me
Imports Me MatrixQCvis, SmartPhos
Suggests Me protti
Links To Me
Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package proDA_1.26.0.tar.gz
Windows Binary (x86_64) proDA_1.26.0.zip
macOS Binary (big-sur-x86_64) proDA_1.26.0.tgz
macOS Binary (sonoma-arm64) proDA_1.26.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/proDA
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/proDA
Package Short Url https://bioconductor.org/packages/proDA/
Package Downloads ReportDownload Stats