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CONSTANd

This is the released version of CONSTANd; for the devel version, see CONSTANd.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13

Data normalization by matrix raking


Bioconductor version: Release (3.23)

Normalizes a data matrix `data` by raking (using the RAS method by Bacharach, see references) the Nrows by Ncols matrix such that the row means and column means equal 1. The result is a normalized data matrix `K=RAS`, a product of row mulipliers `R` and column multipliers `S` with the original matrix `A`. Missing information needs to be presented as `NA` values and not as zero values, because CONSTANd is able to ignore missing values when calculating the mean. Using CONSTANd normalization allows for the direct comparison of values between samples within the same and even across different CONSTANd-normalized data matrices.

Author: Joris Van Houtven [aut, trl], Geert Jan Bex [trl], Dirk Valkenborg [aut, cre]

Maintainer: Dirk Valkenborg <dirk.valkenborg at uhasselt.be>

Citation (from within R, enter citation("CONSTANd")):

Joris Van Houtven, Dirk Valkenborg. CONSTANd: Data normalization by matrix raking. doi:10.18129/B9.bioc.CONSTANd, R package version 1.20.0, https://bioconductor.org/packages/CONSTANd.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("CONSTANd")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("CONSTANd")
CONSTANd HTML R Script
Reference ManualPDF
NEWSText
LICENSEText

Details

biocViews Cheminformatics, DifferentialExpression, Genetics, MassSpectrometry, Normalization, Preprocessing, Proteomics, Software, Transcriptomics
Version1.20.0
In Bioconductor sinceBioC 3.13 (R-4.1) (5.5 years)
License file LICENSE
Depends R (>= 4.1)
Imports
System Requirements
URLqcquan.net/constand
Bug Reportshttps://github.com/PDiracDelta/CONSTANd/issues
See More
Suggests BiocStyle, knitr, rmarkdown, tidyr, ggplot2, gridExtra, magick, Cairo, limma
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package CONSTANd_1.20.0.tar.gz
Windows Binary (x86_64) CONSTANd_1.20.0.zip
macOS Binary (big-sur-x86_64) CONSTANd_1.20.0.tgz
macOS Binary (sonoma-arm64) CONSTANd_1.20.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/CONSTANd
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/CONSTANd
Package Short Url https://bioconductor.org/packages/CONSTANd/
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