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asuri

Analysis of SUrvival and RIsk prediction in patients based on gene signatures

Bioconductor version: 3.23 · Package version: 1.0.0

Other Bioconductor versions

devel is the development version; release is the current stable one.

3.24 (devel), 3.23 (release)

The ASURI (Analysis of SUrvival and patients RIsk prediction based on gene signatures) package discovers marker genes that are related to risk prediction capabilities and to a clinical variable of interest. It uses two main steps, including subsampling glmnet and unicox. The package implements robust functions to discover survival markers related to a clinical phenotype and to predict a risk score, allowing to study the patient's risk based on the gene signatures. Several plots are provided to visualise the relevance of the genes, the risk score, and patient stratification, as well as a robust version of the Kaplan-Meier curves.

DOI: 10.18129/B9.bioc.asuri

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("asuri")

Details

MaintainerAlberto Berral-Gonzalez <aberralgonzalez@gmail.com>
AuthorAlberto Berral-Gonzalez [aut, cre, ctb] (ORCID: <https://orcid.org/0000-0001-8388-6051>), María Sanchez-Martin [aut, ctb] (ORCID: <https://orcid.org/0009-0006-5549-6113>), Santiago Bueno-Fortes [aut, ctb] (ORCID: <https://orcid.org/0000-0001-7141-2860>), Natalia Alonso-Moreda [aut, ctb] (ORCID: <https://orcid.org/0000-0002-2347-5127>), Jose Manuel Sanchez-Santos [aut, ctb] (ORCID: <https://orcid.org/0000-0002-7434-7598>), Manuel Martin-Merino Acera [aut, ctb] (ORCID: <https://orcid.org/0000-0002-5914-2332>), Javier De Las Rivas [aut, ctb] (ORCID: <https://orcid.org/0000-0002-0984-9946>)
LicenseLGPL-3 + file LICENSE
URLhttps://github.com/jdelasrivas-lab/asuri
Bug Reportshttps://github.com/jdelasrivas-lab/asuri/issues
Source branchRELEASE_3_23
Build report Bioconductor build system, r-universe
biocViewsDifferentialExpression, ExonArray, GeneExpression, GenePrediction, Microarray, MultipleComparison, Regression, Software, StatisticalMethod, Survival, WorkflowStep
Package Short Url https://bioconductor.org/packages/asuri/

Citation

From within R, enter citation("asuri"):

Alberto Berral-Gonzalez, María Sanchez-Martin, Santiago Bueno-Fortes, Natalia Alonso-Moreda, Jose Manuel Sanchez-Santos, Manuel Martin-Merino Acera, Javier De Las Rivas. asuri: Analysis of SUrvival and RIsk prediction in patients based on gene signatures. doi:10.18129/B9.bioc.asuri, R package version 1.0.0, https://bioconductor.org/packages/asuri.

Generated from the package metadata; it may differ from the package's own citation.

Documentation

Download

Follow the installation instructions to use this package in your R session.

Source packageasuri_1.0.0.tar.gz
Windows binary (x86_64)asuri_1.0.0.zip
macOS binary (arm64)asuri_1.0.0.tgz
macOS binary (x86_64)asuri_1.0.0.tgz
Dependencies

Depends: R (>= 4.5.0), stats, methods

Imports: SummarizedExperiment, spsUtil, lubridate, survival, glmnet, siggenes, survcomp, scales, ROCR, ggplot2, grDevices, graphics, utils, Rdpack

Suggests: BiocStyle, knitr, formatR, rmarkdown, magick, devtools