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geneRxCluster

This is the released version of geneRxCluster; for the devel version, see geneRxCluster.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13, 3.12, 3.11, 3.10, 3.9, 3.8, 3.7, 3.6, 3.5, 3.4, 3.3, 3.2, 3.1, 3.0, 2.14

gRx Differential Clustering


Bioconductor version: Release (3.23)

Detect Differential Clustering of Genomic Sites such as gene therapy integrations. The package provides some functions for exploring genomic insertion sites originating from two different sources. Possibly, the two sources are two different gene therapy vectors. Vectors are preferred that target sensitive regions less frequently, motivating the search for localized clusters of insertions and comparison of the clusters formed by integration of different vectors. Scan statistics allow the discovery of spatial differences in clustering and calculation of False Discovery Rates (FDRs) providing statistical methods for comparing retroviral vectors. A scan statistic for comparing two vectors using multiple window widths to detect clustering differentials and compute FDRs is implemented here.

Author: Charles Berry

Maintainer: Charles Berry <ccberry at ucsd.edu>

Citation (from within R, enter citation("geneRxCluster")):

Charles Berry. geneRxCluster: gRx Differential Clustering. doi:10.18129/B9.bioc.geneRxCluster, R package version 1.48.0, https://bioconductor.org/packages/geneRxCluster.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("geneRxCluster")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("geneRxCluster")
Using geneRxCluster PDF R Script
Reference ManualPDF

Details

biocViews Clustering, Genetics, Sequencing, Software
Version1.48.0
In Bioconductor sinceBioC 2.14 (R-3.1) (12.5 years)
License GPL (>= 2)
Depends GenomicRanges, IRanges
Imports
System Requirements
URL
See More
Suggests RUnit, BiocGenerics
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package geneRxCluster_1.48.0.tar.gz
Windows Binary (x86_64) geneRxCluster_1.48.0.zip
macOS Binary (big-sur-x86_64) geneRxCluster_1.48.0.tgz
macOS Binary (sonoma-arm64) geneRxCluster_1.48.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/geneRxCluster
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/geneRxCluster
Package Short Url https://bioconductor.org/packages/geneRxCluster/
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