Changes in version 0.99.30 (2019-06-05) + Initial release with Bioconductor + Alignment functions only works on Unix system (For now) + The rest of the pipeline is completely functional for all the OS including windows and MAC_OS Changes in version 0.99.31 (2019-07-17) + Best tunning parameters for SVM functions Changes in version 0.99.42 (2019-08-5) + dataPlots genesBoxplot mode improvements Changes in version 0.99.51 (2019-08-19) + New method web platform added (targetValidation) to retrieve the diseases in the DEGsToDiseases function Changes in version 0.99.55 (2019-10-09) + Several minor bug fixes and enhancements and xgrid/ygrid added to classification plots Changes in version 1.1.15 (2019-11-11) + Novel Biological Based Feature Selection method named as Disease Association Feature Selection (DA-FS) added Changes in version 1.4.5 (2021-04-15) + SVA batch effect correction improved + MAD outliers detection fixed + KnowSeq report updated to include the changes of SVA and MAD modifications + Cross-Validation DEGs Extraction implemented Further versions + Incorporation of RUV to batch effect methods