Changes in version 1.5.14 o Modify Main_mean_NB_spBay. Changes in version 1.5.13 o Activate "Allow sparse matrix as output (valid only for mean version procedure)". Hence you can work on dgCMatrix throughout the process. Input which is not of type dgCMatrix will be converted to dgCMatrix at first. Changes in version 1.5.12 o Deprecated: Allow sparse matrix as output (valid only for mean version procedure). Since sparse matrix is useful only when the matrix it is sparse. o Calibrate documentations. Changes in version 1.5.11 o Allow sparse matrix as output (valid only for mean version procedure). o Let version of RELEASE_3_10 to be 1.4.11. Changes in version 1.5.10 o Update RELEASE_3_10 1.4.2 to 1.4.3. Changes in version 1.5.9 o Change back to Rcpp EstPrior function (sp_mat version). o Use dgCMatrix instead of matrix in R. o define ARMA\_64BIT\_WORD 1 and so on allows for big sparse matrix (learn from the liger R package). Changes in version 1.5.8 o Change back to rowSums instead of using Rcpp EstPrior function. Changes in version 1.5.7 o Add useful function file. o Use Rcpp EstPrior function. Changes in version 1.5.6 o as_matrix for transforming sparse matrix to matrix in R efficiently than as.matrix. Changes in version 1.5.5 o Make BB_fun faster: speed up the access of row of dgCMatrix object. o Modify EstPrior, using rowSums from Matrix package to calculated variance. Hence no need for Rcpp EstPrior function. Changes in version 1.5.4 o Support sparse matrix: dgTMatrix and dgCMatrix. Changes in version 1.5.3 o Add Rcpp EstPrior function. Changes in version 1.5.2 o Vectorize computation in EstPrior function. Changes in version 1.5.0 o Set default setting of BETA_vec=NULL. o Update citation. Changes in version 1.1.6 o Suppress warning message came from BiocParallel. Changes in version 1.1.4 o For a smoother progress bar, use foreach instead of BiocParallel. Changes in version 0.99.19 o Replacing foreach with BiocParallel o Fix some errors in BB_fun Changes in version 0.99.9 o Let more examples to be runnable; Updated vignette; Including SingleCellExperiment Class. Changes in version 0.99.8 o Fix some errors. Changes in version 0.99.4 o Apply corrections proposed by the reviewer, for more details please see Changes in version 0.99.1 o Fix two warnings reported by Bioconductor • WARNING: Use TRUE/FALSE instead of T/F, Found in files: tests/testthat/test-bayNorm.r • WARNING: Use is() or !is() Changes in version 0.99.0 o Pass all checks of both R CMD build and R CMD BiocCheck. o Future work: • Vignette needs to be further improved. • Need to Improve man pages. • Submit to Bioconductor.