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Maaslin2

This is the released version of Maaslin2; for the devel version, see Maaslin2.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13, 3.12, 3.11, 3.10

"Multivariable Association Discovery in Population-scale Meta-omics Studies"


Bioconductor version: Release (3.23)

MaAsLin2 is comprehensive R package for efficiently determining multivariable association between clinical metadata and microbial meta'omic features. MaAsLin2 relies on general linear models to accommodate most modern epidemiological study designs, including cross-sectional and longitudinal, and offers a variety of data exploration, normalization, and transformation methods. MaAsLin2 is the next generation of MaAsLin.

Author: Himel Mallick [aut], Ali Rahnavard [aut], Thomas Kuntz [aut], Sagun Maharjan [aut, cre]

Maintainer: Sagun Maharjan <sagunmaharjann at gmail.com>

Citation (from within R, enter citation("Maaslin2")):

Himel Mallick, Ali Rahnavard, Thomas Kuntz, Sagun Maharjan. Maaslin2: "Multivariable Association Discovery in Population-scale Meta-omics Studies". doi:10.18129/B9.bioc.Maaslin2, R package version 1.26.0, https://bioconductor.org/packages/Maaslin2.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("Maaslin2")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("Maaslin2")
Maaslin2 HTML R Script
Reference ManualPDF
NEWSText
LICENSEText

Details

biocViews Metagenomics, Microbiome, Normalization, Software
Version1.26.0
In Bioconductor sinceBioC 3.10 (R-3.6) (7 years)
License MIT + file LICENSE
Depends R (>= 3.6)
Imports robustbase, biglm, pcaPP, edgeR, metagenomeSeq, pbapply, car, dplyr, vegan, chemometrics, ggplot2, pheatmap, logging, data.table, lmerTest, hash, optparse, grDevices, stats, utils, glmmTMB, MASS, cplm, pscl, lme4, tibble
System Requirements
URLhttp://huttenhower.sph.harvard.edu/maaslin2
Bug Reportshttps://github.com/biobakery/maaslin2/issues
See More
Suggests knitr, testthat (>= 2.1.0), rmarkdown, markdown
Linking To
Enhances
Depends On Me
Imports Me benchdamic, Macarron
Suggests Me ggpicrust2
Links To Me
Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package Maaslin2_1.26.0.tar.gz
Windows Binary (x86_64) Maaslin2_1.26.0.zip
macOS Binary (big-sur-x86_64) Maaslin2_1.26.0.tgz
macOS Binary (sonoma-arm64) Maaslin2_1.26.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/Maaslin2
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/Maaslin2
Package Short Url https://bioconductor.org/packages/Maaslin2/
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