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Clomial

This is the development version of Clomial; for the stable release version, see Clomial.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13, 3.12, 3.11, 3.10, 3.9, 3.8, 3.7, 3.6, 3.5, 3.4, 3.3, 3.2, 3.1, 3.0, 2.14

Infers clonal composition of a tumor


Bioconductor version: Development (3.24)

Clomial fits binomial distributions to counts obtained from Next Gen Sequencing data of multiple samples of the same tumor. The trained parameters can be interpreted to infer the clonal structure of the tumor.

Author: Habil Zare and Alex Hu

Maintainer: Habil Zare <zare at u.washington.edu>

Citation (from within R, enter citation("Clomial")):

Habil Zare and Alex Hu. Clomial: Infers clonal composition of a tumor. doi:10.18129/B9.bioc.Clomial, R package version 1.49.0, https://bioconductor.org/packages/Clomial.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("Clomial")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("Clomial")
A likelihood maximization approach to infer the clonal structure of a cancer using multiple tumor samples PDF R Script
Reference ManualPDF
NEWSText

Details

biocViews Bayesian, Clustering, DNASeq, ExomeSeq, GeneticVariability, Genetics, ImmunoOncology, MultipleComparison, Sequencing, Software, TargetedResequencing
Version1.49.0
In Bioconductor sinceBioC 2.14 (R-3.1) (12.5 years)
License GPL (>= 2)
Depends R (>= 2.10), matrixStats
Imports methods, permute
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package Clomial_1.49.0.tar.gz
Windows Binary (x86_64) Clomial_1.49.0.zip
macOS Binary (big-sur-x86_64) Clomial_1.49.0.tgz
macOS Binary (sonoma-arm64) Clomial_1.49.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/Clomial
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/Clomial
Package Short Url https://bioconductor.org/packages/Clomial/
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