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scRepertoire

A toolkit for single-cell immune receptor profiling


Bioconductor version: Release (3.18)

scRepertoire was built to process data derived from the 10x Genomics Chromium Immune Profiling for both T-cell receptor (TCR) and immunoglobulin (Ig) enrichment workflows and subsequently interacts with the popular Seurat and SingleCellExperiment R packages. It also allows for general analysis of single-cell clonotype information without the use of expression information. The package functions as a wrapper for Startrac and powerTCR R packages.

Author: Nick Borcherding [aut, cre]

Maintainer: Nick Borcherding <ncborch at gmail.com>

Citation (from within R, enter citation("scRepertoire")):

Installation

To install this package, start R (version "4.3") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("scRepertoire")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("scRepertoire")
Using scRepertoire HTML R Script
Reference Manual PDF
NEWS Text

Details

biocViews Annotation, Classification, ImmunoOncology, Sequencing, SingleCell, Software
Version 1.12.0
In Bioconductor since BioC 3.12 (R-4.0) (3.5 years)
License GPL-2
Depends ggplot2, R (>= 4.0)
Imports stringdist, dplyr, reshape2, ggalluvial, stringr, vegan, powerTCR, SingleCellExperiment, SummarizedExperiment, plyr, parallel, doParallel, methods, utils, rlang, igraph, ggraph, tidygraph, SeuratObject
System Requirements
URL
See More
Suggests knitr, rmarkdown, BiocStyle, circlize, scales, Seurat, scater
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package scRepertoire_1.12.0.tar.gz
Windows Binary scRepertoire_1.12.0.zip
macOS Binary (x86_64) scRepertoire_1.12.0.tgz
macOS Binary (arm64) scRepertoire_1.12.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/scRepertoire
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/scRepertoire
Bioc Package Browser https://code.bioconductor.org/browse/scRepertoire/
Package Short Url https://bioconductor.org/packages/scRepertoire/
Package Downloads Report Download Stats