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This is the development version of ASSET; for the stable release version, see ASSET.

An R package for subset-based association analysis of heterogeneous traits and subtypes

Bioconductor version: Development (3.20)

An R package for subset-based analysis of heterogeneous traits and disease subtypes. The package allows the user to search through all possible subsets of z-scores to identify the subset of traits giving the best meta-analyzed z-score. Further, it returns a p-value adjusting for the multiple-testing involved in the search. It also allows for searching for the best combination of disease subtypes associated with each variant.

Author: Samsiddhi Bhattacharjee [aut, cre], Guanghao Qi [aut], Nilanjan Chatterjee [aut], William Wheeler [aut]

Maintainer: Samsiddhi Bhattacharjee <sb1 at>

Citation (from within R, enter citation("ASSET")):


To install this package, start R (version "4.4") and enter:

if (!require("BiocManager", quietly = TRUE))

# The following initializes usage of Bioc devel


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:

ASSET Vignette PDF R Script
Reference Manual PDF


biocViews GenomeWideAssociation, MultipleComparison, SNP, Software, StatisticalMethod
Version 2.23.0
In Bioconductor since BioC 2.13 (R-3.0) (10.5 years)
License GPL-2 + file LICENSE
Depends R (>= 3.5.0), stats, graphics
Imports MASS, msm, rmeta
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Suggests RUnit, BiocGenerics, knitr
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Follow Installation instructions to use this package in your R session.

Source Package ASSET_2.23.0.tar.gz
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macOS Binary (x86_64) ASSET_2.23.0.tgz
macOS Binary (arm64) ASSET_2.23.0.tgz
Source Repository git clone
Source Repository (Developer Access) git clone
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