Bioconductor Developer Survey 2026 Now Open!

HarmonizR

This is the development version of HarmonizR; for the stable release version, see HarmonizR.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18

Handles missing values and makes more data available


Bioconductor version: Development (3.24)

An implementation, which takes input data and makes it available for proper batch effect removal by ComBat or Limma. The implementation appropriately handles missing values by dissecting the input matrix into smaller matrices with sufficient data to feed the ComBat or limma algorithm. The adjusted data is returned to the user as a rebuild matrix. The implementation is meant to make as much data available as possible with minimal data loss.

Author: Simon Schlumbohm [aut, cre], Julia Neumann [aut], Philipp Neumann [aut]

Maintainer: Simon Schlumbohm <schlumbohm at hsu-hh.de>

Citation (from within R, enter citation("HarmonizR")):

Simon Schlumbohm, Julia Neumann, Philipp Neumann. HarmonizR: Handles missing values and makes more data available. doi:10.18129/B9.bioc.HarmonizR, R package version 1.11.0, https://bioconductor.org/packages/HarmonizR.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("HarmonizR")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("HarmonizR")
HarmonizR_Vignette HTML R Script
Reference ManualPDF
NEWSText

Details

biocViews BatchEffect, Software
Version1.11.0
In Bioconductor sinceBioC 3.18 (R-4.3) (3 years)
License GPL-3
Depends R (>= 4.2.0)
Imports doParallel (>= 1.0.16), foreach (>= 1.5.1), janitor (>= 2.1.0), plyr (>= 1.8.6), sva (>= 3.36.0), seriation (>= 1.3.5), limma (>= 3.46.0), SummarizedExperiment
System Requirements
URL
See More
Suggests knitr, rmarkdown, testthat (>= 3.0.0)
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package HarmonizR_1.11.0.tar.gz
Windows Binary (x86_64) HarmonizR_1.11.0.zip (64-bit only)
macOS Binary (big-sur-x86_64) HarmonizR_1.11.0.tgz
macOS Binary (sonoma-arm64) HarmonizR_1.11.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/HarmonizR
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/HarmonizR
Package Short Url https://bioconductor.org/packages/HarmonizR/
Package Downloads ReportDownload Stats