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Modstrings

Working with modified nucleotide sequences

Bioconductor version: 3.24 · Package version: 1.29.0

Other Bioconductor versions

devel is the development version; release is the current stable one.

3.24 (devel), 3.23 (release)

Representing nucleotide modifications in a nucleotide sequence is usually done via special characters from a number of sources. This represents a challenge to work with in R and the Biostrings package. The Modstrings package implements this functionallity for RNA and DNA sequences containing modified nucleotides by translating the character internally in order to work with the infrastructure of the Biostrings package. For this the ModRNAString and ModDNAString classes and derivates and functions to construct and modify these objects despite the encoding issues are implemenented. In addition the conversion from sequences to list like location information (and the reverse operation) is implemented as well.

DOI: 10.18129/B9.bioc.Modstrings

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("Modstrings")

Details

MaintainerFelix G.M. Ernst <felix.gm.ernst@outlook.com>
AuthorFelix G.M. Ernst [aut, cre] (ORCID: <https://orcid.org/0000-0001-5064-0928>), Denis L.J. Lafontaine [ctb, fnd]
LicenseArtistic-2.0
Bug Reportshttps://github.com/FelixErnst/Modstrings/issues
Source branchdevel
Build report Bioconductor build system, r-universe
biocViewsDataImport, DataRepresentation, Infrastructure, Sequencing, Software
Package Short Url https://bioconductor.org/packages/Modstrings/

Citation

From within R, enter citation("Modstrings"):

Felix G.M. Ernst. Modstrings: Working with modified nucleotide sequences. doi:10.18129/B9.bioc.Modstrings, R package version 1.29.0, https://bioconductor.org/packages/Modstrings.

Generated from the package metadata; it may differ from the package's own citation.

Documentation

Download

Follow the installation instructions to use this package in your R session.

Source packageModstrings_1.29.0.tar.gz
Windows binary (x86_64)Modstrings_1.29.0.zip
macOS binary (arm64)Modstrings_1.29.0.tgz
macOS binary (x86_64)Modstrings_1.29.0.tgz
Dependencies

Depends: R (>= 3.6), Biostrings (>= 2.79.3)

Imports: methods, BiocGenerics, GenomicRanges, S4Vectors, IRanges, XVector, stringi, stringr, crayon, grDevices

Suggests: BiocStyle, knitr, rmarkdown, testthat, usethis

Reverse dependencies

Depends On Me (3): EpiTxDb, RNAmodR, tRNAdbImport

Imports Me (1): tRNA

Suggests Me (2): EpiTxDb.Hs.hg38, EpiTxDb.Sc.sacCer3