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MotifPeeker

Benchmarking Epigenomic Profiling Methods Using Motif Enrichment

Bioconductor version: 3.24 · Package version: 1.5.1

Other Bioconductor versions

devel is the development version; release is the current stable one.

3.24 (devel), 3.23 (release)

MotifPeeker is used to compare and analyse datasets from epigenomic profiling methods with motif enrichment as the key benchmark. The package outputs an HTML report consisting of three sections: (1. General Metrics) Overview of peaks-related general metrics for the datasets (FRiP scores, peak widths and motif-summit distances). (2. Known Motif Enrichment Analysis) Statistics for the frequency of user-provided motifs enriched in the datasets. (3. Motif Discovery Enrichment Analysis) Statistics for the frequency of ab-initio discovered motifs enriched in the datasets and compared with known motifs.

DOI: 10.18129/B9.bioc.MotifPeeker

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("MotifPeeker")

Details

MaintainerHiranyamaya Dash <hdash.work@gmail.com>
AuthorHiranyamaya Dash [cre, aut] (ORCID: <https://orcid.org/0009-0005-5514-505X>), Thomas Roberts [aut] (ORCID: <https://orcid.org/0009-0006-6244-8670>), Maria Weinert [aut] (ORCID: <https://orcid.org/0000-0001-6187-1000>), Nathan Skene [aut] (ORCID: <https://orcid.org/0000-0002-6807-3180>)
LicenseGPL (>= 3)
URLhttps://github.com/neurogenomics/MotifPeeker
Bug Reportshttps://github.com/neurogenomics/MotifPeeker/issues
System RequirementsMEME Suite (v5.3.3 or above) <http://meme-suite.org/doc/download.html>
Source branchdevel
Build report Bioconductor build system, r-universe
biocViewsAlignment, ChIPSeq, Epigenetics, FunctionalGenomics, Genetics, MotifDiscovery, MultipleComparison, QualityControl, SequenceMatching, Software
Package Short Url https://bioconductor.org/packages/MotifPeeker/

Citation

From within R, enter citation("MotifPeeker"):

Hiranyamaya Dash, Thomas Roberts, Maria Weinert, Nathan Skene. MotifPeeker: Benchmarking Epigenomic Profiling Methods Using Motif Enrichment. doi:10.18129/B9.bioc.MotifPeeker, R package version 1.5.1, https://bioconductor.org/packages/MotifPeeker.

Generated from the package metadata; it may differ from the package's own citation.

Documentation

Download

Follow the installation instructions to use this package in your R session.

Source packageMotifPeeker_1.5.1.tar.gz
macOS binary (arm64)MotifPeeker_1.5.1.tgz
macOS binary (x86_64)MotifPeeker_1.5.1.tgz
Dependencies

Depends: R (>= 4.5.0)

Imports: BiocFileCache, BiocParallel, DT, ggplot2, plotly, universalmotif, GenomicRanges, IRanges, rtracklayer, tools, htmltools, rmarkdown, viridis, SummarizedExperiment, htmlwidgets, Rsamtools, GenomicAlignments, Seqinfo, Biostrings, BSgenome, memes, S4Vectors, dplyr, purrr, tidyr, heatmaply, stats, utils

Suggests: BSgenome.Hsapiens.UCSC.hg19, BSgenome.Hsapiens.UCSC.hg38, BSgenome.Mmusculus.UCSC.mm10, BSgenome.Mmusculus.UCSC.mm39, downloadthis, knitr, markdown, methods, remotes, rworkflows, testthat (>= 3.0.0), withr, emoji, curl, jsonlite