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This is the development version of Oscope; for the stable release version, see Oscope.

Oscope - A statistical pipeline for identifying oscillatory genes in unsynchronized single cell RNA-seq

Bioconductor version: Development (3.20)

Oscope is a statistical pipeline developed to identifying and recovering the base cycle profiles of oscillating genes in an unsynchronized single cell RNA-seq experiment. The Oscope pipeline includes three modules: a sine model module to search for candidate oscillator pairs; a K-medoids clustering module to cluster candidate oscillators into groups; and an extended nearest insertion module to recover the base cycle order for each oscillator group.

Author: Ning Leng

Maintainer: Ning Leng <lengning1 at>

Citation (from within R, enter citation("Oscope")):


To install this package, start R (version "4.4") and enter:

if (!require("BiocManager", quietly = TRUE))

# The following initializes usage of Bioc devel


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:

Oscope_vigette PDF R Script
Reference Manual PDF


biocViews GeneExpression, ImmunoOncology, RNASeq, Sequencing, Software, StatisticalMethod
Version 1.35.0
In Bioconductor since BioC 3.2 (R-3.2) (8.5 years)
License Artistic-2.0
Depends EBSeq, cluster, testthat, BiocParallel
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Source Package Oscope_1.35.0.tar.gz
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