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ProteinBatcher

This is the development version of ProteinBatcher; to use it, please install the devel version of Bioconductor.

An end-to-end proteomics workflow with condition-aware imputation, flexible statistical modelling and interactive visualization

Bioconductor version: 3.24 · Package version: 0.99.7

ProteinBatcher provides utilities to read, validate, and harmonize quantitative proteomics result tables generated by DIA-NN from data-independent acquisition mass spectrometry experiments. The package enables batch processing of multiple DIA-NN output files, consistent handling of protein identifiers and associated metadata, and transformation of tabular data into analysis-ready formats. It facilitates downstream differential abundance analysis using linear modeling frameworks based on limma, with explicit support for multivariable experimental designs including batch effects and other confounding covariates, as well as correlation-aware designs via duplicateCorrelation.

Author: Aitor Moruno-Cuenca [aut, cre] ORCID iD ORCID: 0009-0009-8133-2552 , Dr. Sergi Sayols-Puig [ctb] ORCID iD ORCID: 0000-0002-3877-4170 , Dr. Bruna Oriol-Tordera [ctb] ORCID iD ORCID: 0000-0002-2714-9097 , Dr. Hiba Salim [dtc] ORCID iD ORCID: 0000-0002-2168-0258 , Dr. Francesc Fernández-Albert [ths] ORCID iD ORCID: 0000-0001-5561-0701 , Prof. Dr. Alexandre Perera-Lluna [ths] ORCID iD ORCID: 0000-0001-6427-851X , Dr. Guadalupe Espadas-García [ctb, dtc] ORCID iD ORCID: 0000-0002-6415-8013 , Dr. Elisa Monzón-Casanova [ctb, fnd] ORCID iD ORCID: 0000-0001-6617-6138 , Prof. Dr. Eduard Sabidó-Aguade [res, ctb, dtc, fnd] ORCID iD ORCID: 0000-0001-6506-7714

Maintainer: Aitor Moruno-Cuenca <morunoaitor at gmail.com>

DOI: 10.18129/B9.bioc.ProteinBatcher

Citation

From within R, enter citation("ProteinBatcher"):

Aitor Moruno-Cuenca. ProteinBatcher: An end-to-end proteomics workflow with condition-aware imputation, flexible statistical modelling and interactive visualization. doi:10.18129/B9.bioc.ProteinBatcher, R package version 0.99.7, https://bioconductor.org/packages/ProteinBatcher.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("ProteinBatcher")

For older versions of R, please refer to the appropriate Bioconductor release.

Details

Version0.99.7
LicenseMIT + file LICENSE
URLhttps://github.com/DataScienceRD-Almirall/ProteinBatcher
Bug Reportshttps://github.com/DataScienceRD-Almirall/ProteinBatcher/issues
Last updated2026-08-21
In Bioconductor sinceBioC 3.24 (R-4.6)
Downloads rank2436 of 2,456
Source branchdevel
Build report Bioconductor build system, r-universe
biocViewsBatchEffect, DataImport, DataRepresentation, MassSpectrometry, Proteomics, Software
Package Short Url https://bioconductor.org/packages/ProteinBatcher/

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("ProteinBatcher")
ProteinBatcher workflow HTML R Script
Reference ManualPDF
NEWSText

Download

Follow the installation instructions to use this package in your R session.

Source packageProteinBatcher_0.99.7.tar.gz
Windows binary (x86_64)ProteinBatcher_0.99.7.zip
macOS binary (arm64)ProteinBatcher_0.99.7.tgz
macOS binary (x86_64)ProteinBatcher_0.99.7.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/ProteinBatcher
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/ProteinBatcher
Package Downloads ReportDownload Stats
Dependencies

Imports: data.table, ggplot2, ggrepel, grDevices, grid, limma, methods, S4Vectors, stats, SummarizedExperiment, utils

Suggests: knitr, rmarkdown, testthat (>= 3.0.0)