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This is the development version of ReactomeGSA; for the stable release version, see ReactomeGSA.

Client for the Reactome Analysis Service for comparative multi-omics gene set analysis

Bioconductor version: Development (3.20)

The ReactomeGSA packages uses Reactome's online analysis service to perform a multi-omics gene set analysis. The main advantage of this package is, that the retrieved results can be visualized using REACTOME's powerful webapplication. Since Reactome's analysis service also uses R to perfrom the actual gene set analysis you will get similar results when using the same packages (such as limma and edgeR) locally. Therefore, if you only require a gene set analysis, different packages are more suited.

Author: Johannes Griss [aut, cre]

Maintainer: Johannes Griss <johannes.griss at>

Citation (from within R, enter citation("ReactomeGSA")):


To install this package, start R (version "4.4") and enter:

if (!require("BiocManager", quietly = TRUE))

# The following initializes usage of Bioc devel


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:

Analysing single-cell RNAseq data HTML R Script
Loading and re-analysing public data through ReactomeGSA HTML R Script
Using the ReactomeGSA package HTML R Script
Reference Manual PDF


biocViews GeneExpression, GeneSetEnrichment, Proteomics, Reactome, Software, SystemsBiology, Transcriptomics
Version 1.19.0
In Bioconductor since BioC 3.10 (R-3.6) (4.5 years)
License MIT + file LICENSE
Imports jsonlite, httr, progress, ggplot2, methods, gplots, RColorBrewer, dplyr, tidyr, Biobase
System Requirements
Bug Reports
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Suggests testthat, knitr, rmarkdown,, devtools
Linking To
Enhances limma, edgeR, Seurat (>= 3.0), scater
Depends On Me
Imports Me
Suggests Me
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Follow Installation instructions to use this package in your R session.

Source Package ReactomeGSA_1.19.0.tar.gz
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macOS Binary (x86_64) ReactomeGSA_1.19.0.tgz
macOS Binary (arm64) ReactomeGSA_1.19.0.tgz
Source Repository git clone
Source Repository (Developer Access) git clone
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