Bioconductor Developer Survey 2026 Now Open!

betterChromVAR

Improved ChromVAR (Chromatin Variation Across Regions)

Bioconductor version: 3.24 · Package version: 1.1.10

Other Bioconductor versions

devel is the development version; release is the current stable one.

3.24 (devel), 3.23 (release)

A much faster analytical implementation of chromVAR, with additional features, used to infer TF activity from (bulk or single-cell) ATAC-seq data and motif annotations (or binding probabilities). The package also includes the CVnorm normalization method based on the chromVAR logic.

DOI: 10.18129/B9.bioc.betterChromVAR

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("betterChromVAR")

Details

MaintainerPierre-Luc Germain <pierre-luc.germain@hest.ethz.ch>
AuthorPierre-Luc Germain [aut, cre] (ORCID: <https://orcid.org/0000-0003-3418-4218>)
LicenseGPL (>= 3)
URLhttps://github.com/plger/betterChromVAR
Bug Reportshttps://github.com/plger/betterChromVAR/issues
Source branchdevel
Build report Bioconductor build system, r-universe
biocViewsATACSeq, Epigenetics, Normalization, Sequencing, Software
Package Short Url https://bioconductor.org/packages/betterChromVAR/

Citation

From within R, enter citation("betterChromVAR"):

Pierre-Luc Germain. betterChromVAR: Improved ChromVAR (Chromatin Variation Across Regions). doi:10.18129/B9.bioc.betterChromVAR, R package version 1.1.10, https://bioconductor.org/packages/betterChromVAR.

Generated from the package metadata; it may differ from the package's own citation.

Documentation

Download

Follow the installation instructions to use this package in your R session.

Source packagebetterChromVAR_1.1.10.tar.gz
Windows binary (x86_64)betterChromVAR_1.1.10.zip
macOS binary (arm64)betterChromVAR_1.1.10.tgz
macOS binary (x86_64)betterChromVAR_1.1.10.tgz
Dependencies

Depends: R (>= 4.1.0), SummarizedExperiment

Imports: BiocParallel, BiocNeighbors, Biostrings, DelayedMatrixStats, GenomicRanges, IRanges, Matrix, matrixStats, sparseMatrixStats, MatrixGenerics, methods, S4Vectors, stats

Suggests: BiocStyle, knitr, rmarkdown, sessioninfo, testthat