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cpvSNP

This is the development version of cpvSNP; for the stable release version, see cpvSNP.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13, 3.12, 3.11, 3.10, 3.9, 3.8, 3.7, 3.6, 3.5, 3.4, 3.3, 3.2, 3.1

Gene set analysis methods for SNP association p-values that lie in genes in given gene sets


Bioconductor version: Development (3.24)

Gene set analysis methods exist to combine SNP-level association p-values into gene sets, calculating a single association p-value for each gene set. This package implements two such methods that require only the calculated SNP p-values, the gene set(s) of interest, and a correlation matrix (if desired). One method (GLOSSI) requires independent SNPs and the other (VEGAS) can take into account correlation (LD) among the SNPs. Built-in plotting functions are available to help users visualize results.

Author: Caitlin McHugh, Jessica Larson, and Jason Hackney

Maintainer: Caitlin McHugh <mchughc at uw.edu>

Citation (from within R, enter citation("cpvSNP")):

Caitlin McHugh, Jessica Larson, and Jason Hackney. cpvSNP: Gene set analysis methods for SNP association p-values that lie in genes in given gene sets. doi:10.18129/B9.bioc.cpvSNP, R package version 1.45.0, https://bioconductor.org/packages/cpvSNP.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("cpvSNP")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("cpvSNP")
Running gene set analyses with the "cpvSNP" package PDF R Script
Reference ManualPDF
NEWSText

Details

biocViews GeneSetEnrichment, Genetics, GenomicVariation, Pathways, Software, StatisticalMethod
Version1.45.0
In Bioconductor sinceBioC 3.1 (R-3.2) (11.5 years)
License Artistic-2.0
Depends R (>= 3.5.0), GenomicFeatures, GSEABase (>= 1.24.0)
Imports methods, corpcor, BiocParallel, ggplot2, plyr
System Requirements
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Suggests TxDb.Hsapiens.UCSC.hg19.knownGene, RUnit, BiocGenerics, ReportingTools, BiocStyle
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package cpvSNP_1.45.0.tar.gz
Windows Binary (x86_64) cpvSNP_1.45.0.zip
macOS Binary (big-sur-x86_64) cpvSNP_1.45.0.tgz
macOS Binary (sonoma-arm64) cpvSNP_1.45.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/cpvSNP
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/cpvSNP
Package Short Url https://bioconductor.org/packages/cpvSNP/
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