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enrichmet

This is the development version of enrichmet; to use it, please install the devel version of Bioconductor.

enrichmet: R package for Quick and Easy Pathway and Network Analyses in Metabolomics


Bioconductor version: Development (3.24)

Provides functions to perform metabolite-based pathway enrichment analysis using Fisher's exact test and MetSEA. Computes relative betweenness centrality (RBC) of input metabolites in a pathway-metabolite interaction network. The package generates visualizations including pathway dot plots, MetSEA plots, metabolite centrality plots, and network plots. It supports KEGG-based pathway inputs and generates exportable results.

Author: Yonatan Mekonnen [aut, cre] ORCID iD ORCID: 0000-0002-7430-9428 , H. Lee Moffitt Cancer Center & Research Institute [fnd] (Grant number: P01CA250984)

Maintainer: Yonatan Mekonnen <yaayalew at gmail.com>

Citation (from within R, enter citation("enrichmet")):

Yonatan Mekonnen. enrichmet: enrichmet: R package for Quick and Easy Pathway and Network Analyses in Metabolomics. doi:10.18129/B9.bioc.enrichmet, R package version 0.99.18, https://bioconductor.org/packages/enrichmet.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("enrichmet")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("enrichmet")
enrichmet: Pathway and Network Analysis for Metabolomics Tutorial HTML
Reference ManualPDF
NEWSText

Details

biocViews KEGG, Metabolomics, Network, NetworkEnrichment, Pathways, Software, Visualization
Version0.99.18
In Bioconductor sinceBioC 3.24 (R-4.6)
License AGPL-3 + file LICENSE
Depends R (>= 4.5.0)
Imports BiocFileCache, methods, circlize, ComplexHeatmap, curl, data.table, dplyr, fgsea, ggplot2, ggraph, ggrepel, igraph, limma, openxlsx, qvalue, rlang, scales, stats, stringr, tibble, tidyr, utils, SummarizedExperiment
System Requirements
URLhttps://github.com/biodatalab/enrichmet
Bug Reportshttps://github.com/biodatalab/enrichmet/issues
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Suggests knitr, rmarkdown, BiocStyle, testthat (>= 3.2.0), withr
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package
Windows Binary (x86_64)
macOS Binary (big-sur-x86_64)
macOS Binary (sonoma-arm64)
Source Repositorygit clone https://git.bioconductor.org/packages/enrichmet
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/enrichmet
Package Short Url https://bioconductor.org/packages/enrichmet/
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