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fCCAC

functional Canonical Correlation Analysis to evaluate Covariance between nucleic acid sequencing datasets

Bioconductor version: 3.24 · Package version: 1.39.0

Other Bioconductor versions

devel is the development version; release is the current stable one.

3.24 (devel), 3.23 (release)

Computational evaluation of variability across DNA or RNA sequencing datasets is a crucial step in genomics, as it allows both to evaluate reproducibility of replicates, and to compare different datasets to identify potential correlations. fCCAC applies functional Canonical Correlation Analysis to allow the assessment of: (i) reproducibility of biological or technical replicates, analyzing their shared covariance in higher order components; and (ii) the associations between different datasets. fCCAC represents a more sophisticated approach that complements Pearson correlation of genomic coverage.

DOI: 10.18129/B9.bioc.fCCAC

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("fCCAC")

Details

MaintainerPedro Madrigal <pmadrigal@ebi.ac.uk>
AuthorPedro Madrigal [aut, cre] (ORCID: <https://orcid.org/0000-0003-1959-8199>)
LicenseArtistic-2.0
URLhttps://github.com/pmb59/fCCAC
Bug Reportshttps://github.com/pmb59/fCCAC/issues
Source branchdevel
Build report Bioconductor build system, r-universe
biocViewsATACSeq, ChIPSeq, Coverage, Epigenetics, FunctionalGenomics, MNaseSeq, RNASeq, Sequencing, Software, Transcription
Package Short Url https://bioconductor.org/packages/fCCAC/

Citation

From within R, enter citation("fCCAC"):

Pedro Madrigal. fCCAC: functional Canonical Correlation Analysis to evaluate Covariance between nucleic acid sequencing datasets. doi:10.18129/B9.bioc.fCCAC, R package version 1.39.0, https://bioconductor.org/packages/fCCAC.

Generated from the package metadata; it may differ from the package's own citation.

Download

Follow the installation instructions to use this package in your R session.

Source packagefCCAC_1.39.0.tar.gz
Windows binary (x86_64)fCCAC_1.39.0.zip
macOS binary (arm64)fCCAC_1.39.0.tgz
macOS binary (x86_64)fCCAC_1.39.0.tgz
Dependencies

Depends: R (>= 4.2.0), S4Vectors, IRanges, GenomicRanges, grid

Imports: fda, RColorBrewer, genomation, ggplot2, ComplexHeatmap, grDevices, stats, utils

Suggests: RUnit, BiocGenerics, BiocStyle, knitr, rmarkdown