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This is the development version of methylCC; for the stable release version, see methylCC.

Estimate the cell composition of whole blood in DNA methylation samples

Bioconductor version: Development (3.20)

A tool to estimate the cell composition of DNA methylation whole blood sample measured on any platform technology (microarray and sequencing).

Author: Stephanie C. Hicks [aut, cre] , Rafael Irizarry [aut]

Maintainer: Stephanie C. Hicks <shicks19 at>

Citation (from within R, enter citation("methylCC")):


To install this package, start R (version "4.4") and enter:

if (!require("BiocManager", quietly = TRUE))

# The following initializes usage of Bioc devel


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:

The methylCC user's guide HTML R Script
Reference Manual PDF


biocViews DNAMethylation, MethylSeq, MethylationArray, Microarray, Sequencing, Software, WholeGenome
Version 1.19.0
In Bioconductor since BioC 3.10 (R-3.6) (4.5 years)
License GPL-3
Depends R (>= 3.6), FlowSorted.Blood.450k
Imports Biobase, GenomicRanges, IRanges, S4Vectors, dplyr, magrittr, minfi, bsseq, quadprog, plyranges, stats, utils, bumphunter, genefilter, methods, IlluminaHumanMethylation450kmanifest, IlluminaHumanMethylation450kanno.ilmn12.hg19
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Suggests rmarkdown, knitr, testthat (>= 2.1.0), BiocGenerics, BiocStyle, tidyr, ggplot2
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Follow Installation instructions to use this package in your R session.

Source Package methylCC_1.19.0.tar.gz
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macOS Binary (x86_64) methylCC_1.19.0.tgz
macOS Binary (arm64) methylCC_1.19.0.tgz
Source Repository git clone
Source Repository (Developer Access) git clone
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