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This is the development version of qsmooth; for the stable release version, see qsmooth.

Smooth quantile normalization

Bioconductor version: Development (3.20)

Smooth quantile normalization is a generalization of quantile normalization, which is average of the two types of assumptions about the data generation process: quantile normalization and quantile normalization between groups.

Author: Stephanie C. Hicks [aut, cre] , Kwame Okrah [aut], Koen Van den Berge [ctb], Hector Corrada Bravo [aut] , Rafael Irizarry [aut]

Maintainer: Stephanie C. Hicks <shicks19 at>

Citation (from within R, enter citation("qsmooth")):


To install this package, start R (version "4.4") and enter:

if (!require("BiocManager", quietly = TRUE))

# The following initializes usage of Bioc devel


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The qsmooth user's guide HTML R Script
Reference Manual PDF


biocViews BatchEffect, Microarray, MultipleComparison, Normalization, Preprocessing, RNASeq, Sequencing, Software
Version 1.21.0
In Bioconductor since BioC 3.9 (R-3.6) (5 years)
License GPL-3
Depends R (>= 4.0)
Imports SummarizedExperiment, utils, sva, stats, methods, graphics, Hmisc
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Suggests bodymapRat, quantro, knitr, rmarkdown, BiocStyle, testthat
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Source Package qsmooth_1.21.0.tar.gz
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