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segmenter

Perform Chromatin Segmentation Analysis in R by Calling ChromHMM

Bioconductor version: 3.24 · Package version: 1.19.0

Other Bioconductor versions

devel is the development version; release is the current stable one.

3.24 (devel), 3.23 (release)

Chromatin segmentation analysis transforms ChIP-seq data into signals over the genome. The latter represents the observed states in a multivariate Markov model to predict the chromatin's underlying states. ChromHMM, written in Java, integrates histone modification datasets to learn the chromatin states de-novo. The goal of this package is to call chromHMM from within R, capture the output files in an S4 object and interface to other relevant Bioconductor analysis tools. In addition, segmenter provides functions to test, select and visualize the output of the segmentation.

DOI: 10.18129/B9.bioc.segmenter

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("segmenter")

Details

MaintainerMahmoud Ahmed <mahmoud.s.fahmy@students.kasralainy.edu.eg>
AuthorMahmoud Ahmed [aut, cre] (ORCID: <https://orcid.org/0000-0002-4377-6541>)
LicenseGPL-3
Bug Reportshttps://github.com/MahShaaban/segmenter/issues
Source branchdevel
Build report Bioconductor build system, r-universe
biocViewsHistoneModification, Software
Package Short Url https://bioconductor.org/packages/segmenter/

Citation

From within R, enter citation("segmenter"):

Mahmoud Ahmed. segmenter: Perform Chromatin Segmentation Analysis in R by Calling ChromHMM. doi:10.18129/B9.bioc.segmenter, R package version 1.19.0, https://bioconductor.org/packages/segmenter.

Generated from the package metadata; it may differ from the package's own citation.

Documentation

Download

Follow the installation instructions to use this package in your R session.

Source packagesegmenter_1.19.0.tar.gz
Windows binary (x86_64)segmenter_1.19.0.zip
macOS binary (arm64)segmenter_1.19.0.tgz
macOS binary (x86_64)segmenter_1.19.0.tgz
Dependencies

Depends: R (>= 4.1)

Imports: ChIPseeker, GenomicRanges, SummarizedExperiment, IRanges, S4Vectors, bamsignals, ComplexHeatmap, graphics, stats, utils, methods, chromhmmData

Suggests: testthat, knitr, rmarkdown, TxDb.Hsapiens.UCSC.hg18.knownGene, Gviz