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sigvar

This is the development version of sigvar; to use it, please install the devel version of Bioconductor.

Quantify and visualize variability of mutational signatures within and across samples

Bioconductor version: 3.24 · Package version: 0.99.8

This package allows users to import mutational signature attribution (a.k.a. exposure) matrices and compute, visualize, and test their variabilities within and across samples.

Author: Maike Morrison [aut] ORCID iD ORCID: 0000-0003-0430-1401 , Nicolas Alcala [aut, cre] ORCID iD ORCID: 0000-0002-5961-5064 , Worldwide Cancer Research [fnd] (Grant 24-0106), French Ligue Nationale Contre le Cancer [fnd]

Maintainer: Nicolas Alcala <alcalan at iarc.who.int>

DOI: 10.18129/B9.bioc.sigvar

Citation

From within R, enter citation("sigvar"):

Maike Morrison, Nicolas Alcala. sigvar: Quantify and visualize variability of mutational signatures within and across samples. doi:10.18129/B9.bioc.sigvar, R package version 0.99.8, https://bioconductor.org/packages/sigvar.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("sigvar")

For older versions of R, please refer to the appropriate Bioconductor release.

Details

Version0.99.8
LicenseMIT + file LICENSE
URLhttps://github.com/MaikeMorrison/sigvar
Bug Reportshttps://github.com/MaikeMorrison/sigvar/issues
Last updated2026-07-17
In Bioconductor sinceBioC 3.24 (R-4.6)
Downloads rank2436 of 2,456
Source branchdevel
Build report Bioconductor build system, r-universe
biocViewsDataImport, DriverMutation, Software, SomaticMutation, StatisticalMethod, StructuralVariation, Visualization, WholeGenome
Package Short Url https://bioconductor.org/packages/sigvar/

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("sigvar")
Introduction to Signature Variability Analysis with sigvar HTML R Script
Reference ManualPDF
NEWSText

Download

Follow the installation instructions to use this package in your R session.

Source packagesigvar_0.99.8.tar.gz
Windows binary (x86_64)sigvar_0.99.8.zip
macOS binary (arm64)sigvar_0.99.8.tgz
macOS binary (x86_64)sigvar_0.99.8.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/sigvar
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/sigvar
Package Downloads ReportDownload Stats
Dependencies

Depends: R (>= 4.5)

Imports: dplyr, readr, ggplot2, rlang, tidyr, stringr, ggh4x, glue, ggtext, ggforce, scales, GenomicFeatures, GenomeInfoDb, BSgenome, Biostrings, rtracklayer, TxDb.Hsapiens.UCSC.hg38.knownGene, TxDb.Mmusculus.UCSC.mm10.knownGene, lifecycle, withr

Suggests: knitr, rmarkdown, testthat (>= 3.0.0), magick, BiocStyle, BSgenome.Hsapiens.UCSC.hg38, PNWColors, cowplot, ggpubr, ggrepel, kableExtra, lsa, patchwork, tidyverse